Research Article
NCCAM/NCI Phase 1 Study of Mistletoe Extract and Gemcitabine in Patients with Advanced Solid Tumors
Table 1
(a) Study population demographics. (b) Prior treatment by disease type*.
| (a) |
| | | Stage I () | Stage II () | Total () | Total (%) |
| | Number enrolled | 20 | 24 | 44 | — | | Age (years) | | | | | | Mean | 55.0 | 55.1 | 55.1 | — | | Range | 29–81 | 29–76 | 29–81 | — | | Gender | | | | | | Male | 10 | 13 | 23 | 52% | | Female | 10 | 11 | 21 | 48% | | Race | | | | | | White | 17 | 19 | 36 | 82% | | Black | 2 | 2 | 4 | 9% | | Asian | 0 | 3 | 3 | 7% | | Ethnicity | | | | | | Not Hispanic | 17 | 24 | 41 | 93% | | Hispanic | 3 | 0 | 3 | 7% | | Cancer diagnosis | | | | | | Colorectal | 4 | 13 | 17 | 39% | | Breast | 6 | 6 | 12 | 27% | | Pancreatic | 6 | 4 | 10 | 23% | | Lung | 4 | 1 | 5 | 11% | | Disease stage | | | | | | IV | 20 | 24 | 44 | 100% |
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| (b) |
| | Disease type | No prior treatment | Chemotherapy only | Radiation only | Chemotherapy and radiation | Chemotherapy and surgery | Chemotherapy, surgery, and radiation | Total |
| | Colorectal | 0 | 4 | 0 | 1 | 8 | 4 | 17 | | Breast | 0 | 1 | 0 | 0 | 1 | 10 | 12 | | Pancreatic | 9 | 0 | 0 | 1 | 0 | 0 | 10 | | Lung | 1 | 1 | 1 | 2 | 0 | 0 | 5 |
| | Total (/%) | 10 (22.7%) | 6 (13.6%) | 1 (2.3%) | 4 (9.1%) | 9 (20.5%) | 14 (31.8%) | 44 |
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No study participants were treated solely with surgery or with surgery plus radiation only.
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