Effects of Acupuncture on 1-Chloro-2,4-dinitrochlorobenzene-Induced Atopic Dermatitis

Figure 5

Suppression of MAP kinase expression by acupuncture at the meridian point LI11. Phosphorylation of ERK1/2, JNK, and p38 MAP kinases was significantly elevated by DNCB sensitization. Acupuncture treatment on the meridian point significantly suppressed the expression of MAP kinases. NOR: mice treated with vehicle; DNCB: mice sensitized with DNCB; LP: mice sensitized with DNCB and treated at local points around the lesion; MP: mice sensitized with DNCB and treated at meridian point LI11. ^∗∗𝑃<0.01, ^∗∗∗𝑃<0.001, compared to the NOR group; ^##𝑃<0.01, ^###𝑃<0.001, compared to the DNCB group; ^§§𝑃<0.01, ^§§§𝑃<0.001, compared to the LP group. One-way ANOVA followed by the Newman-Keuls test was performed for statistical analysis, and all data are presented as the mean ± S.D.

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