Protective Effects of Rooibos (Aspalathus linearis) and/or Red Palm Oil (Elaeis guineensis) Supplementation on tert-Butyl Hydroperoxide-Induced Oxidative Hepatotoxicity in Wistar Rats

Table 9

Effects of aqueous rooibos extract, RPO, and/or their combination on markers of lipid peroxidation in the plasma and liver of all experimental rats.

Treatment	Plasma		Liver
	CD (nmol/L)	MDA; (µmol MDA/L)	CD; (nmol/g tissue)	MDA; (µmol MDA/g tissue)
Negative control (water)	71.67 ± 2.43	2.44 ± 0.09	7.29 ± 0.15	0.37 ± 0.09
Positive control (t-BHP)	89.75 ± 1.30*	2.72 ± 0.16	8.98 ± 0.12*	0.62 ± 0.04**
RTE	72.60 ± 1.24	2.55 ± 0.07	7.54 ± 0.17	0.10 ± 0.01*
RPO	108.89 ± 13.4*	2.52 ± 0.11	7.50 ± 0.12	0.10 ± 0.004*
RTE + RPO	102.11 ± 4.91*	2.49 ± 0.07	7.44 ± 0.17	0.11± 0.003*
RTE + t-BHP	101.69 ± 5.18^#	2.61 ± 0.11	7.56 ± 0.21^#	0.10 ± 0.01^*#
RPO + t-BHP	103.67 ± 4.67^#	2.45 ± 0.13	7.98 ± 0.22^#	0.16 ± 0.06^*#
RTE + RPO + t-BHP	106.83 ± 2.15^#	2.42 ± 0.09	7.79 ± 0.11^#	0.11 ± 0.01^*#

Values in columns are mean ± SEM of 8–10 rats per group. *Significantly different from negative control (𝑃<0.05). **Marginally different from negative control (𝑃<0.1). ^#Significantly different from positive control (𝑃<0.05). CD: conjugated diene, MDA: malondialdehyde, RTE: aqueous rooibos extract, RPO: red palm oil, t-BHP: tert-butyl hydroperoxide.