Evidence-Based Complementary and Alternative Medicine / 2013 / Article / Tab 1

Review Article

Recent Advances on the Use of Biochemical Extracts as Filaricidal Agents

Table 1

Bioproduct with reported filaricidal activity.

NameFamilyPart usedExtraction methodFilarial pathogenDosageReference

Azadirachta indica MeliaceaeLeafOrganic solvent and water fractionationTeladorsagia circumcincta 3.1–50 mg/mL[12]
FlowerDistilled ethanol
Distilled water
Setaria cervi 5–25 ng/mL[17]
Andrographis paniculata AcanthaceaeLeafWater decoctionDipetalonema reconditum0.06 mL/Kg[30]
LeafAqueous extractB. malayi 0.5–10 mg/mL[31]
Heliclona oculata ChalinidaeSpongesMethanol extract solvents fractionationB. malayi 100 mg/Kg[16]
Haliclona exigua ChalinidaeSpongesmethanolic extract and butanol fractionB. malayi 15.6–31.2 µm/mL[26]
Trachyspermum ammi L.ApiaceaeFruitsMethanolic extractSetaria digitata
B. malayi
0.01–0.5 mg/mL[27]
Ricinus communis EuphorbiaceaeSeedMethanolic extract ethanol fractionationB. malayi
S. digitata
10–100 µg/mL
1 mg/mL
Morinda citrifolia RubiaceaeFruitsAqueous extractW. bancrofti 0.02–0.04 noni : media[34]
Xylocarpus granatum MeliaceaeLeafEthanolic extract
Aqueous extract
B. malayi
B. pahangi
100 mg/kg
0.5–10 mg/mL
Hibiscus sabdariffa Malvaceae LeafEthanolic extractB. malayi 500 mg–1 g/mL[8]