Concurrent Use of Hypnotic Drugs and Chinese Herbal Medicine Therapies among Taiwanese Adults with Insomnia Symptoms: A Population-Based Study

Table 4

Number (no.) of new cases, population-at-risk, and incidence rates and hazard ratios (HR); 95% confidence intervals (CI) for hip fracture estimated from multivariate Cox regression model on a random sample of the National Health Insurance Research Database among sample subjects and followed from 2002 to 2008.

Presence of hip fracture during the follow-up period	Hypnotic users without using Chinese medicine, no. cases/population	Hypnotic users coprescribed Chinese medicine, no. cases/population	Hypnotic users coprescribed Chinese medicine/hypnotic users without using Chinese medicine
			HR	(95% CI)
Numbers of hip fractures among hypnotic users	152/5,848	294/19,994	0.57	(0.47–0.69)
≥30 days; Incidence rate per 1,000 person-years	123/5,045; 6.5	260/17,149; 3.4	0.62	(0.50–0.77)
<30 days; Incidence rate per 1,000 person-years	29/803; 11.1	34/2,845; 2.9	0.33	(0.20–0.54)