Research Article

Qigong Exercise Alleviates Fatigue, Anxiety, and Depressive Symptoms, Improves Sleep Quality, and Shortens Sleep Latency in Persons with Chronic Fatigue Syndrome-Like Illness

Table 2

Sleep, fatigue, anxiety, and depressive symptoms at baseline, immediate postintervention, and 3-month postintervention.

Within-group effectsBetween-group effects
T0 T1aEffect sizeT2aEffect sizeT1 − T0bT2 − T0bTime × groupc
Mean (SD)Mean (SD)Cohen’s Mean (SD)Cohen’s Mean (SD)Mean (SD) value

PSQI total
 Qigong ()10.0 (3.7)8.2 (3.4)∗∗∗−0.518.3 (3.4)∗∗∗−0.48−1.9 (3.4)−1.7 (3.4)2.777 0.064
 Waitlist () 10.2 (3.8)9.5 (3.7)−0.199.3 (3.5)−0.25−0.7 (2.6)−0.9 (3.5)
Subjective sleep quality
 Qigong ()1.93 (0.71)1.42 (0.74)∗∗∗−0.701.49 (0.73)∗∗∗−0.61−0.51 (0.71)∗∗−0.45 (0.7)∗∗6.3640.002
 Waitlist ()1.86 (0.71)1.68 (0.69)−0.26 1.75 (0.70)−0.16 −0.18 (0.67) −0.11 (0.72)
Sleep latency
 Qigong ()1.63 (1.06)1.23 (0.99)∗∗∗−0.391.28 (1.02)∗∗∗−0.34−0.40 (0.75)−0.35 (0.81)3.1680.044
 Waitlist ()1.69 (0.97) 1.57 (0.92)−0.13 1.49 (0.95)−0.21 −0.12 (0.70) −0.20 (0.79)
Sleep duration
 Qigong ()1.67 (0.91)1.44 (0.83)−0.261.40 (0.81)∗∗−0.31−0.23 (0.80)−0.27 (0.72)1.9050.151
 Waitlist ()1.75 (0.84)1.79 (0.89)−0.05 1.61 (0.85)−0.17 0.04 (0.81) −0.13 (0.83)
Sleep efficiency
 Qigong ()0.87 (1.16)0.72 (1.09)−0.130.96 (1.26)0.07−0.15 (1.32)0.09 (1.29)0.651 0.522
 Waitlist ()1.09 (1.12)0.79 (1.15)−0.261.05 (1.26)−0.03−0.31 (0.97)−0.04 (1.41)
Sleep disturbance
 Qigong ()1.64 (0.69)1.40 (0.62)∗∗∗−0.371.36 (0.63)∗∗∗−0.42−0.24 (0.52)−0.28 (0.48)2.802 0.062
 Waitlist ()1.73 (0.68) 1.63 (0.65)−0.15 1.63 (0.61)−0.15−0.11 (0.61) −0.11 (0.63)
Use of sleep medication
 Qigong ()0.31 (0.78)0.28 (0.77)−0.040.30 (0.75)−0.01−0.03 (0.83)−0.01 (0.80)0.220 0.803
 Waitlist () 0.26 (0.60)0.32 (0.72)0.090.34 (0.79)0.110.05 (0.72) 0.08 (0.89)
Daytime dysfunction
 Qigong ()1.90 (0.82)1.59 (0.94)−0.351.52 (0.96)−0.43−0.32 (0.86)−0.38 (0.92)1.381 0.253
 Waitlist () 1.77 (0.77)1.64 (0.75)−0.171.53 (0.73)−0.32−0.12 (0.76) −0.23 (0.83)
ChFS total
 Qigong ()37.4 (6.2)25.6 (12.6)∗∗∗−1.1925.2 (12.7)∗∗∗−1.22−11.8 (11.4)∗∗∗−12.2 (11.9)∗∗∗16.650<0.001
 Waitlist () 36.4 (8.3) 32.3 (9.7)∗∗∗−0.45 31.1 (10.9)∗∗∗−0.55 −4.1 (6.5) −5.3 (7.8)
ChFS physical
 Qigong ()24.2 (4.0)16.7 (8.0)∗∗∗−1.1916.2 (8.1)∗∗∗−1.25−7.5 (7.3)∗∗∗−8.0 (7.5)∗∗∗18.527<0.001
 Waitlist () 23.0 (5.0) 20.6 (5.9)∗∗∗−0.44 20.0 (6.7)∗∗∗−0.51−2.4 (4.1)−3.1 (5.0)
ChFS mental
 Qigong ()13.2 (3.6)9.0 (5.4)∗∗∗−0.929.0 (5.3)∗∗∗−0.93−4.3 (4.9)∗∗∗−4.3 (5.0)∗∗9.290<0.001
 Waitlist () 13.3 (4.5)11.7 (4.6)∗∗∗−0.3511.2 (4.9)∗∗∗−0.45−1.7 (3.4)−2.2 (3.7)
HADS Anxiety
 Qigong ()10.9 (3.7)8.5 (4.0)∗∗∗−0.628.8 (4.4)∗∗∗−0.52−2.3 (3.2)∗∗−2.1 (3.7)4.172 0.016
 Waitlist () 11.2 (3.6)10.4 (4.0)−0.2110.2 (4.0)−0.26−0.8 (3.3)−1.0 (3.3)
HADS depression
 Qigong ()9.4 (3.5)6.6 (3.7)∗∗∗−0.787.2 (4.1)∗∗∗−0.58−2.7 (3.5)∗∗∗−2.1 (3.9)10.262<0.001
 Waitlist () 9.5 (3.4)8.8 (3.9)−0.198.5 (4.0)∗∗−0.27−0.7 (2.9)−1.0 (3.0)

PSQI: Pittsburgh Sleep Quality Index; ChFS: Chalder Fatigue Scale; HADS: Hospital Anxiety and Depression Scale; SD: standard deviation; T0: baseline; T1: immediate postintervention; T2: 3-month postintervention.
aCompared with baseline using paired -test; bcompared the change score between groups using independent -test; crepeated measures ANCOVA adjusting for between-group difference in gender ratio. , and .