Protective Effect of Sundarban Honey against Acetaminophen-Induced Acute Hepatonephrotoxicity in Rats

Table 1

The effects of APAP and honey on serum hepatic biomarkers among control and treated rats.

Parameters	Treatment				Percentage change
	Control	Control + honey	Honey + APAP	APAP	Control + honey	Honey + APAP	APAP
ALP (IU/L)	182.81 ± 0.00	190.91 ± 23.31^•	192.89 ± 0.00^#	315.09 ± 14.16^*	4.43%	5.51%	72.36%
ALT (IU/L)	32.69 ± 0.59	32.54 ± 0.54	73.17 ± 2.22^#	146.49 ± 0.00^*	−0.45%	123.83%	348.12%
AST (IU/L)	108.27 ± 1.01	100.12 ± 0.00	168.85 ± 0.00^#	268.98 ± 1.27^*	−7.53%	55.95%	148.43%
TB (mg/dL)	0.63 ± 0.03	0.65 ± 0.03	0.74 ± 0.01^#	1.36 ± 0.00^*	3.17%	17.46%	115.87%
TP (g/dL)	3.27 ± 0.03	3.55 ± 0.23^•	3.41 ± 0.12^#	3.19 ± 0.01^*	8.56%	4.28%	−2.45%

Each value is the mean obtained for six rats ± SD; ^*symbol in each row indicating the significant difference between control and APAP group; ^•symbol in each row indicating the significant difference between control and control + honey group; ^#symbol in each row indicating the significant difference between APAP and honey + APAP at . Percentage change is calculated as 100 × [(value of treatment − value of control)/value of control].