Protective Effect of Sundarban Honey against Acetaminophen-Induced Acute Hepatonephrotoxicity in Rats

Table 2

The effects of APAP and honey on serum renal biomarkers among control and treated rats.

Parameters	Treatment				Percentage change
	Control	Control + honey	Honey + APAP	APAP	Control + honey	Honey + APAP	APAP
Creatinine (mg/dL)	0.73 ± 0.03	0.72 ± 0.02	0.74 ± 0.01^#	0.93 ± 0.03^*	−1.37%	1.37%	27.39%
Urea (mg/dL)	30.57 ± 2.21	30.43 ± 2.09	31.23 ± 1.41^#	47.88 ± 0.97^*	−0.46%	2.16%	56.62%

Each value is the mean obtained for six rats ± SD; ^*symbol in each row indicating the significant difference between control and APAP group; ^#symbol in each row indicating the significant difference between APAP and honey + APAP at . Percentage change is calculated as 100 × [(value of treatment − value of control)/value of control].