Ameliorative Effect of Hexane Extract of Phalaris canariensis on High Fat Diet-Induced Obese and Streptozotocin-Induced Diabetic Mice

Table 12

Effect of hexane extract of P. canariensis on antioxidant enzyme activities of normal and diabetic mice.

Parameters	Normal C	SD C	MD C	SD + AL-H	MD + AL-H	SD + GB
SOD—liver	7.54±2.19	3.79±0.82^a	4.05±1.38^b	5.87±0.89^b	6.01±1.05^b	6.80±0.41^c
SOD—kidney	13.82±3.51	7.35±1.37^a	8.36±2.53^b	10.24±2.63^b	11.47±3.41^b	13.025±1.57^b
SOD—pancreas	54.52±5.21	36.47±3.28^a	35.99±5.42^b	43.88±5.39^b	46.90±5.48^b	50.71±4.36^b
CAT—liver	82.36±6.17	44.53±3.13^a	47.32±7.14^b	64.56±6.38^b	67.12±6.74^b	70.26±2.16^b
CAT—kidney	35.61±2.33	20.76±1.65^a	22.01±9.53^c	29.56±2.81^c	32.07±2.53^c	34.17±1.79^b
CAT—pancreas	59.32±5.38	25.56±4.19^a	23.19±5.46^a	40.24±3.67^a	43.79±5.18^a	47.83±4.36^c
GSH—liver	47.68±7.12	21.80±1.97^a	29.15±6.36^b	36.52±4.86^b	39.48±4.36^b	42.38±2.28^b
GSH—kidney	24.45±3.71	5.79±2.06^a	7.21±3.53^b	15.29±3.83^b	17.20±3.53^b	19.27±3.58^b
GSH—pancreas	12.48±3.39	5.19±0.94^a	7.42±2.56^b	6.91±1.80^b	8.47±1.56^b	10.79±1.92^b
GPx—liver	7.26±1.59	4.31±1.30^a	5.39±2.01^b	5.35±1.83^b	5.64±1.87^b	5.92±1.26^b
GPx—kidney	5.92±1.42	3.53±0.92^a	3.40±1.43^b	4.53±1.34^b	4.60±1.73^b	4.78±0.94^b
GPx—pancreas	4.64±1.19	2.32±0.36^a	3.42±1.26^b	3.31±0.61^b	3.70±1.26^b	3.89±0.27^b

All values are expressed as mean ± SEM, 𝑛=6 values. ^a𝑃<0.01 when compared to normal control group; ^b𝑃<0.01, ^c𝑃<0.05 compared to diabetic control group, where the significance was performed by Oneway ANOVA followed by post hoc Dunnett’s test. Glibenclamide (GB). Control (C); the values are given in U/mg of protein.