Evidence-Based Complementary and Alternative Medicine / 2014 / Article / Tab 4 / Review Article
The Complementary and Alternative Medicine for Endometriosis: A Review of Utilization and Mechanism Table 4 Chinese traditional patent medicine for EM treatment in literatures.
Chinese traditional patent medicine; sample/case number (
) Control; sample/case number (
) Total clinical effect rate: total effect rate (
)*; dysmenorrhoea alleviation rate (
); Pregnancy rate (
) Model used Therapeutic effects and actions References Guizhi Fuling Capsules;
Mifepristone Tablets;
: 83.3% verus 87.5%Human study CA125↓ EMAb↓ [102 ] Guizhi Fuling Capsules SD rat model CD+3↑ CD+4↑ CD+4/CD+8↑, CD+8↓ [103 , 104 ] Sanjie Zhentong Capsules;
Danazol;
: 92.9 % verus 77.5%Human study Alleviate dysmenorrhoea Shrink endometrioic lesion [105 ] Recurrence rate ↓ [106 ] Yiweikang Granule;
0 Danazol;
: 84.0% verus 86.0%Human study CA125↓ VEGF↓ E2↓ Alleviate dysmenorrhoea Shrink endometrioic lesion [107 , 108 ] Dahuang Zhechong Wan;
Danazol;
: 80.8% verus 86.7%Human study EMAb ↓ Alleviate dysmenorrhoea Shrink endometrioic lesion [109 ] Dahuang Zhechong Wan Danazol SD rat model E2↓ PRL↓ P↑ [110 ] Xiang Leng Wan;
Medroxyprogesterone Acetate Dispersible;
Human study CA125↓ Alleviate dysmenorrhoea [111 ] Xiang Leng Wan Danazol SD rat model IL-8↓ TNF-
↓ [112 ]
Total effect rate (
) = all effective number of cases/total number of cases; effective case refers to the patients or animal models whose signs and symptoms have been improved after treatment.