Protective Effect of Danhong Injection on Acute Hepatic Failure Induced by Lipopolysaccharide and D-Galactosamine in Mice

Table 1

Effect of DHI on ALT, AST, and GST activities and MDA and TBil concentrations.

Group	Dose	ALT (U/I)	AST (U/I)	MDA (nmol/mg prot)	GST (U/mL)	TBil (mg/dL)
Control		62.14±5.94	172.20±29.91	0.06±0.01	328.25±35.46	0.22±0.02
D-GalN/LPS		2541.86±788.81^††	452.76±120.13^†	0.30±0.06^†	527.85±95.64^†	0.55±0.02^†
NAC (mg/kg)	300	423.52±62.77^∗∗	343.31±51.20	0.29±0.03	499.53±93.41	0.46±0.04^∗
DHI (mL/kg)	1.5	997.16±227.95^∗	346.80±80.59	0.20±0.02	557.36±79.22	0.38±0.04^∗
	3	94.94±15.51^∗∗	173.51±25.51^∗∗	0.19±0.01	302.69±42.85^∗	0.28±0.04^∗∗
	6	159.53±51.86^∗∗	230.88±40.15	0.20±0.02	562.44±70.96	0.51±0.070

Data show mean ± SEM (𝑛=8).
†,†† indicate significance from the control group at 𝑃<0.05 and 𝑃<0.01 probability level, respectively; ∗,∗∗ indicate significance from the GalN/LPS group at 𝑃<0.05 and 𝑃<0.01 probability level.