Finding Inhibitors of Mutant Superoxide Dismutase-1 for Amyotrophic Lateral Sclerosis Therapy from Traditional Chinese Medicine

Table 1

Results of TCM compounds interacted with mutant SOD1 structure by LigandFit docking analysis.

Name	-PLP1	-PLP2	-PMF	DOCK SCORE
Hesperidin	33.72	39.61	95.25	91.91
THSG	37.36	41.61	101.23	88.16
Hyperoside	32.16	41.58	79.96	79.85
Dopamine*	26.79	30.68	37.71	51.94
Nobiletin	44.73	44.01	109.57	41.14
Ursolic acid	36.61	36.50	114.59	34.69
Tangeretin	29.24	32.45	73.20	33.28
Nobiletin	59.41	46.54	117.14	29.82
Lupeol	42.26	42.03	115.03	23.97
Emodin	30.29	32.13	84.07	22.02
Physcion	39.79	37.57	98.34	19.94

∗Control.