Effects of Chronic Electroacupuncture on Depression- and Anxiety-Like Behaviors in Rats with Chronic Neuropathic Pain

Figure 6

Effects of EA at GV20–GB34 on the phosphorylation of hippocampus NR1 subunits. (a) Representative western blots showing the expression of pNR1, total NR1, and GAPDH in contralateral hippocampus. (b) Chronic EA treatment at GV20–GB34 significantly reversed the CCI induced low level of pNR1 in the hippocampus, but the sham EA treatment had no effects on NR1 phosphorylation. (c) There was no significant difference in the expression of total NR1 among rats subjected to different treatments (𝑛=3). The data are expressed as the mean±SEM. (^∗𝑃<0.05 versus normal group. ^#𝑃<0.05 versus model group as control).

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