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Evidence-Based Complementary and Alternative Medicine
Volume 2014, Article ID 167253, 10 pages
http://dx.doi.org/10.1155/2014/167253
Research Article

Pharmacokinetic Comparative Study of Gastrodin and Rhynchophylline after Oral Administration of Different Prescriptions of Yizhi Tablets in Rats by an HPLC-ESI/MS Method

1School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China
2Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084, China

Received 15 August 2014; Revised 13 November 2014; Accepted 21 November 2014; Published 18 December 2014

Academic Editor: Cheorl-Ho Kim

Copyright © 2014 Zhaohui Ge et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. D. Bensky, A. Gamble, and T. Kaptchuk, Chinese Herbal Medicine: Material Medica, Eastland Press, Berkeley, Calif, USA, 1999.
  2. Y. Shimada, K. Terasawa, T. Yamamoto, I. Maruyama, Y. Saitoh, and E. Kanaki, “A well-controlled study of Choto-san and placebo in the treatment of vascular dementia,” Journal of Traditional Medicine, vol. 11, pp. 17–26, 1994. View at Google Scholar
  3. Committee of Pharmacopoeia of P.R. China, Chinese Pharmacopoeia. Part I, Chemical Industry Press, Beijing, China, 2010.
  4. Z. W. Ma, Y. F. Liu, C. Ji, and W. P. Cheng, “A review on treating Parkinson disease in TCM,” Clinical Journal of Chinese Medicine, vol. 3, pp. 120–122, 2011. View at Google Scholar
  5. D. Yuan, B. Ma, J.-Y. Yang et al., “Anti-inflammatory effects of rhynchophylline and isorhynchophylline in mouse N9 microglial cells and the molecular mechanism,” International Immunopharmacology, vol. 9, no. 13-14, pp. 1549–1554, 2009. View at Publisher · View at Google Scholar · View at Scopus
  6. D. Yuan, B. Ma, C. Wu et al., “Alkaloids from leaves of Uncaria rhychophylla and their inhibitory activity on NO production in lipopolysaccharide-activated microglia,” Journal of Natural Products, vol. 71, no. 7, pp. 1271–1274, 2008. View at Publisher · View at Google Scholar · View at Scopus
  7. Q. Zheng, P.-F. Yue, B. Wu, P.-Y. Hu, Z.-F. Wu, and M. Yang, “Pharmacokinetics comparative study of a novel Chinese traditional herbal formula and its compatibility,” Journal of Ethnopharmacology, vol. 137, no. 1, pp. 221–225, 2011. View at Publisher · View at Google Scholar · View at Scopus
  8. L. L. Li, Z. R. Zhang, T. Gong, L. L. He, and L. Deng, “Simultaneous determination of Gastrodin and Ligustrazine hydrochloride in dog plasma by gradient high-performance liquid chromatography,” Journal of Pharmaceutical and Biomedical Analysis, vol. 41, no. 4, pp. 1083–1087, 2006. View at Publisher · View at Google Scholar · View at Scopus
  9. W. Zhang, Y. X. Sheng, and J. L. Zhang, “Determination and pharmacokinetics of gastrodin and p-hydroxybenzylalcohol after oral administration of Gastrodia elata Bl. extract in rats by HPLC-ESI/MS method,” Phytomedicine, vol. 15, pp. 844–850, 2008. View at Google Scholar
  10. X. H. Ju, Y. Shi, N. Liu, D. M. Guo, and X. Cui, “Determination and pharmacokinetics of gastrodin in human plasma by HPLC coupled with photodiode array detector,” Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, vol. 878, no. 22, pp. 1982–1986, 2010. View at Publisher · View at Google Scholar · View at Scopus
  11. L.-C. Lin, Y.-F. Chen, W.-C. Lee, Y.-T. Wu, and T.-H. Tsai, “Pharmacokinetics of gastrodin and its metabolite p-hydroxybenzyl alcohol in rat blood, brain and bile by microdialysis coupled to LC-MS/MS,” Journal of Pharmaceutical and Biomedical Analysis, vol. 48, no. 3, pp. 909–917, 2008. View at Publisher · View at Google Scholar · View at Scopus
  12. K. X. Liu, G. Z. Han, Y. L. Chang, C. Y. Su, N. Y. Tang, and Y. R. Chen, “Simultaneous determination of gastrodin and its metabolite by HPLC,” Biomedical Chromatography, vol. 2, no. 1, pp. 17–19, 1987. View at Publisher · View at Google Scholar · View at Scopus
  13. G. W. Lu, Y. J. Zou, Q. Z. Mo, J. Huang, D. Q. Chu, and D. Y. Ye, “Circadian rhythm of [3H] gastrodin pharmacokinetics in rats,” Acta Pharmacologica Sinica, vol. 7, pp. 190–191, 1986. View at Google Scholar
  14. Q. Wang, G. Chen, and S. Zeng, “Distribution and metabolism of gastrodin in rat brain,” Journal of Pharmaceutical and Biomedical Analysis, vol. 46, no. 2, pp. 399–404, 2008. View at Publisher · View at Google Scholar · View at Scopus
  15. L. Jiang, J. Dai, Z. Huang, Q. Du, J. Lin, and Y. Wang, “Simultaneous determination of gastrodin and puerarin in rat plasma by HPLC and the application to their interaction on pharmacokinetics,” Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, vol. 915-916, pp. 8–12, 2013. View at Publisher · View at Google Scholar · View at Scopus
  16. H. Kushida, M. Fukutake, M. Tabuchi et al., “Simultaneous quantitative analyses of indole and oxindole alkaloids of Uncaria Hook in rat plasma and brain after oral administration of the traditional Japanese medicine Yokukansan using high-performance liquid chromatography with tandem mass spectrometry,” Biomedical Chromatography, vol. 27, no. 12, pp. 1647–1656, 2013. View at Publisher · View at Google Scholar · View at Scopus
  17. B. Ma, G. B. Sun, H. B. Xu, M. Li, Z. H. Yang, and X. B. Sun, “Rhynchophylline in rat blood by high-performance liquid chromatography-coupled microdialysis,” Journal of Medicinal Plants Research, vol. 6, no. 15, pp. 2977–2984, 2012. View at Publisher · View at Google Scholar
  18. W. Wang, C.-M. Ma, and M. Hattori, “Metabolism and pharmacokinetics of rhynchophylline in rats,” Biological and Pharmaceutical Bulletin, vol. 33, no. 4, pp. 669–676, 2010. View at Publisher · View at Google Scholar · View at Scopus
  19. J. Z. Cai, C. L. Lin, J. S. Ma, L. F. Hu, G. Y. Lin, and X. Q. Wang, “Determination of rhynchophylline in rat plasma by liquid chromatography mass spectrometry and its application,” Journal of Chromatographic Science, vol. 52, no. 7, pp. 661–665, 2013. View at Publisher · View at Google Scholar
  20. Z. Y. Chen, X. Wang, X. Q. Li, X. Y. Wang, and W. G. Zhang, “Distribution of isorhynchophyline in liver tissues before and after compatibility with gastrodin and isorhynchophylline in rats,” Zhongguo Shiyan Fangjixue Zazhi, vol. 18, pp. 193–196, 2012. View at Google Scholar