Evidence-Based Complementary and Alternative Medicine / 2014 / Article / Tab 1

Research Article

Amelioration of Diabetes and Painful Diabetic Neuropathy by Punica granatum L. Extract and Its Spray Dried Biopolymeric Dispersions

Table 1

Acute effect of P. granatum ethanolic extract (Pg), F1, F2, and gallic acid (GA) on blood glucose of alloxan-induced diabetic mice (n = 7).

GroupDose (mg/kg)Mean blood glucose concentration ± SEM (mg/dL)
0 hr0.5 hr2 hr6 hr

Diabetic control202.79 ± 5.60211.93 ± 4.50214.21 ± 9.70 210.15 ± 7.30
GB5219.70 ± 3.70223.64 ± 1.80159.74 ± 2.10130.64 ± 2.40**
Pg 25218.29 ± 1.50142.44 ± 2.80181.56 ± 2.02138.89 ± 1.45*
Pg 50200.43 ± 2.10240.93 ± 2.50158.41 ± 2.60131.96 ± 1.90*
Pg 100249.92 ± 1.80292.44 ± 2.80228.56 ± 2.02128.98± 1.54*
Placebo F1200208.10 ± 3.10227.23 ± 2.10222.62 ± 2.30209.98 ± 2.90
F150243.12 ± 1.30158.44 ± 1.90167.65 ± 2.10144.33 ± 2.00*
F1100201.33 ± 1.70130.44 ± 2.10160.89 ± 2.90120.77 ± 2.10*
F1200263.11 ± 2.90139.56 ± 2.40117.79 ± 2.80125.33 ± 2.30*
Placebo F2200213.56 ± 3.10202.17 ± 2.60201.13 ± 2.80229.56 ± 3.10
F250211.55 ± 2.90205.12 ± 1.30146.82 ± 1.40147.725 ± 2.80*
F2100214.65 ± 1.30213.99 ± 1.90186.83 ± 1.10123.27 ± 1.20*
F2200240.44 ± 2.50190.825 ± 1.90172.165 ± 1.80142.87 ± 2.20*
GA3201.29 ± 5.60210.43 ± 4.50213.71 ± 9.70 209.05 ± 7.30
GA6202.20 ± 3.70222.14 ± 1.80158.24 ± 2.10129.14 ± 2.40**
GA12218.29 ± 1.50142.44 ± 2.80181.56 ± 2.02138.89 ± 1.45*

SEM: standard error of the mean.
P < 0.05 significant from the control animals.
P < 0.01 significant from the control animals.

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