Evidence-Based Complementary and Alternative Medicine / 2014 / Article / Tab 2

Research Article

Amelioration of Diabetes and Painful Diabetic Neuropathy by Punica granatum L. Extract and Its Spray Dried Biopolymeric Dispersions

Table 2

Subacute effect of Pg, F1, F2, and GA on blood glucose of alloxan-induced diabetic mice (n = 7).

GroupDose (mg/kg)Mean blood glucose concentration ± SEM (mg/dL)
1st day3rd day5th day8th day

Control107.90 ± 2.50109.80 ± 3.60108.86 ± 3.20117.50 ± 4.70
Diabetic controla202.79 ± 5.60***211.93 ± 4.50***214.91 ± 9.70***210.55 ± 7.30***
GBb5186.70 ± 3.70179.53 ± 2.90161.54 ± 2.40**171.97 ± 3.10
Pg b25138.67 ± 2.6087.54 ± 1.70158.63 ± 2.30135.50 ± 2.10**
Pg b50143.34 ± 1.90119.67 ± 1.70119.33 ± 1.90119.10 ± 1.10**
Pg b100132.12 ± 1.30112.98 ± 2.50124.36 ± 2.60111.50 ± 2.50*
Placebo F1200193.10 ± 3.10212.66 ± 2.90229.54 ± 2.80226.33 ± 2.10
F1b50144.11 ± 1.20129.40 ± 1.60130.66 ± 2.40125.88 ± 3.10*
F1b100120.33 ± 1.70115.60 ± 2.40128.65 ± 2.90124.33 ± 3.20*
F1b200125.21 ± 2.90115.50 ± 3.10108.40 ± 2.40104.32 ± 1.90*
Placebo F2200229.33 ± 2.50226.89 ± 2.90204.98 ± 3.10265.44 ± 2.90
F2b50175.50 ± 2.50119.90 ± 2.10119.10 ± 1.30118.50 ± 1.90*
F2b100118.65 ± 1.30128.10 ± 1.30122.49 ± 2.40117.65 ± 2.10*
F2b200191.33 ± 3.9094.54 ± 1.40108.55 ± 3.40107.43 ± 2.50*
GAb3198.10 ± 1.90208.00 ± 2.20111.36 ± 3.30101.88 ± 2.22*
GAb6179.65 ± 3.10134.66 ± 2.60130.54 ± 2.9098.23 ± 2.87*
GAb12168.33 ± 2.90140.50 ± 3.50137.25 ± 2.70118.55 ± 3.50*

SEM: standard error of the mean.
P < 0.05 significant from the control animals.
P < 0.01 significant from the control animals.
P < 0.001 significant from the control animals.
Compared to vehicle control.
Compared to diabetic control.

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