Traditional Chinese Medicine Shuang Shen Ning Xin Attenuates Myocardial Ischemia/Reperfusion Injury by Preserving of Mitochondrial Function

Figure 6

Effect of SSNX on mitochondrial permeability transition in cardiac tissue after MI/R injury. (a) Ca²⁺-induced mitochondrial swelling measured as decrease in the initial optical density (OD520) within 10 min. Note: cyclosporin A (CsA) is an mPTP inhibitor. (b) Mean changes in the initial optical density (OD520) at 10 min. Data are shown as mean ± SD, 𝑛=6/group. ^##𝑃<0.01 versus sham group; ^∗𝑃<0.05 and ^∗∗𝑃<0.01 versus I/R group.

(a)

(b)