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Evidence-Based Complementary and Alternative Medicine
Volume 2014, Article ID 187036, 12 pages
http://dx.doi.org/10.1155/2014/187036
Research Article

Alleviative Effects of a Kampo (a Japanese Herbal) Medicine “Maoto (Ma-Huang-Tang)” on the Early Phase of Influenza Virus Infection and Its Possible Mode of Action

1Department of Drug Discovery Sciences, Kitasato Institute for Life Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan
2Graduate School of Infection Control Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan
3Oriental Medicine Research Center, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8642, Japan

Received 25 November 2013; Revised 17 January 2014; Accepted 25 January 2014; Published 20 March 2014

Academic Editor: Ken Yasukawa

Copyright © 2014 Takayuki Nagai et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [16 citations]

The following is the list of published articles that have cited the current article.

  • Xue-qian Peng, Hui-fen Zhou, Yu-yan Zhang, Jie-hong Yang, Hai-tong Wan, and Yu He, “Antiviral effects of Yinhuapinggan granule against influenza virus infection in the ICR mice model,” Journal of Natural Medicines, 2015. View at Publisher · View at Google Scholar
  • Tatsuya Shirahata, Takayuki Nagai, Nozomu Hirata, Masaki Yokoyama, Tatsuya Katsumi, Naruki Konishi, Takashi Nishino, Kazuishi Makino, Haruki Yamada, Eisuke Kaji, Hiroaki Kiyohara, and Yoshinori Kobayashi, “Syntheses and mucosal adjuvant activity of simplified oleanolic acid saponins possessing cinnamoyl ester,” Bioorganic & Medicinal Chemistry, 2016. View at Publisher · View at Google Scholar
  • Hidemasa Nakaminami, Hideaki Ikoshi, Norihisa Noguchi, Tetsuya Yamada, Takeaki Wajima, and Kaho Kobayashi, “The modified Gingyo-san, a Chinese herbal medicine, has direct antibacterial effects against respiratory pathogens,” BMC Complementary and Alternative Medicine, vol. 16, no. 1, 2016. View at Publisher · View at Google Scholar
  • Xue-qian Peng, Hui-fen Zhou, Yi-yu Lu, Jun-kui Chen, Hai-tong Wan, and Yu-yan Zhang, “Protective effects of Yinhuapinggan granule on mice with influenza viral pneumonia,” International Immunopharmacology, vol. 30, pp. 85–93, 2016. View at Publisher · View at Google Scholar
  • Nongluk Sriwilaijaroen, Hiroaki Hiramatsu, Riku Shirayama, Masaki Shoji, Takashi Kuzuhara, and Yasuo Suzuki, “Inhibition of PA endonuclease activity of influenza virus RNA polymerase by Kampo medicines,” Drug Discoveries & Therapeutics, vol. 10, no. 2, pp. 109–113, 2016. View at Publisher · View at Google Scholar
  • Meng-Meng Xiao, Chun-Shui Pan, Yu-Ying Liu, Li-Qian Ma, Li Yan, Jing-Yu Fan, Chuan-She Wang, Rong Huang, and Jing-Yan Han, “Post-treatment with Ma-Huang-Tang ameliorates cold-warm-cycles induced rat lung injury,” Scientific Reports, vol. 7, no. 1, 2017. View at Publisher · View at Google Scholar
  • Takashi Matsumoto, Hirotaka Kushida, Shoko Matsushita, Yoshiyuki Oyama, Takafumi Suda, Junko Watanabe, Yoshio Kase, and Mitsutoshi Setou, “Distribution Analysis via Mass Spectrometry Imaging of Ephedrine in the Lungs of Rats Orally Administered the Japanese Kampo Medicine Maoto,” Scientific Reports, vol. 7, pp. 44098, 2017. View at Publisher · View at Google Scholar
  • Akinori Nishi, Katsuya Ohbuchi, Hirotaka Kushida, Takashi Matsumoto, Keiko Lee, Haruo Kuroki, Shigeki Nabeshima, Chika Shimobori, Nagisa Komokata, Hitomi Kanno, Naoko Tsuchiya, Makoto Zushi, Tomohisa Hattori, Masahiro Yamamoto, Yoshio Kase, Yukiko Matsuoka, and Hiroaki Kitano, “Deconstructing the traditional Japanese medicine “Kampo”: compounds, metabolites and pharmacological profile of maoto, a remedy for flu-like symptoms,” npj Systems Biology and Applications, vol. 3, no. 1, 2017. View at Publisher · View at Google Scholar
  • Byung-Wook Lee, Hyeon-Yeop Lee, Kwang-Ho Heo, Hyun-Woo Cho, Man-Suk Hwang, In Heo, Byung-Cheul Shin, and Eui-Hyoung Hwang, “Analysis of herbal medicine prescriptions for patients in an academic Korean medical hospital: A cross sectional study of electronic medical records (2010–2013),” Chinese Journal of Integrative Medicine, 2017. View at Publisher · View at Google Scholar
  • Haider Abdul-Lateef Mousa, “Prevention and Treatment of Influenza, Influenza-Like Illness, and Common Cold by Herbal, Complementary, and Natural Therapies,” Journal of Evidence-Based Complementary & Alternative Medicine, vol. 22, no. 1, pp. 166–174, 2017. View at Publisher · View at Google Scholar
  • Shinta Masui, Shigeki Nabeshima, Kazuhiko Ajisaka, Kei Yamauchi, Ryuta Itoh, Kazunari Ishii, Toshinori Soejima, and Kenji Hiromatsu, “Maoto, a Traditional Japanese Herbal Medicine, Inhibits Uncoating of Influenza Virus,” Evidence-Based Complementary and Alternative Medicine, vol. 2017, pp. 1–12, 2017. View at Publisher · View at Google Scholar
  • Akihiko Komuro, “Kampo Medicines for Infectious Diseases,” Japanese Kampo Medicines for the Treatment of Common Diseases: Focus on Inflammation, pp. 127–142, 2017. View at Publisher · View at Google Scholar
  • Haitong Wan, Wenyang Wei, Yiyu Lu, Yu He, Xueqian Peng, and Huifen Zhou, “Antiviral effects of Ma Huang Tang against H1N1 influenza virus infection in vitro and in an ICR pneumonia mouse model,” Biomedicine and Pharmacotherapy, vol. 102, pp. 1161–1175, 2018. View at Publisher · View at Google Scholar
  • Hai-xia Du, Hui-fen Zhou, Hao-fang Wan, Jie-hong Yang, Yi-yu Lu, Yu He, and Hai-tong Wan, “Antiviral effects and mechanisms of Yinhuapinggan granule against H1N1 influenza virus infection in RAW264.7 cells,” Inflammopharmacology, 2018. View at Publisher · View at Google Scholar
  • Ken Watanabe, “ Drug-Repositioning Approach for the Discovery of Anti-Influenza Virus Activity of Japanese Herbal (Kampo) Medicines In Vitro : Potent High Activity of Daio-Kanzo-To ,” Evidence-Based Complementary and Alternative Medicine, vol. 2018, pp. 1–9, 2018. View at Publisher · View at Google Scholar
  • Hiroyuki Kitagawa, Katsuya Ohbuchi, Masaya Munekage, Kazune Fujisawa, Yasuhiro Kawanishi, Tsutomu Namikawa, Hirotaka Kushida, Takashi Matsumoto, Chika Shimobori, Akinori Nishi, Chiharu Sadakane, Junko Watanabe, Masahiro Yamamoto, and Kazuhiro Hanazaki, “Phenotyping analysis of the Japanese Kampo medicine maoto in healthy human subjects using wide-targeted plasma metabolomics,” Journal of Pharmaceutical and Biomedical Analysis, 2018. View at Publisher · View at Google Scholar