Alleviative Effects of a Kampo (a Japanese Herbal) Medicine “Maoto (Ma-Huang-Tang)” on the Early Phase of Influenza Virus Infection and Its Possible Mode of Action
Figure 3
Effects of maoto extract and oseltamivir on the rectal temperature of upper respiratory tract influenza virus-infected mice. A/J mice were mock infected (◆) or infected (□) intranasally with mouse-adapted influenza virus A/PR/8/34, and the rectal temperature was measured for 120 hours (a). The influenza virus-infected mice were administered orally with water (□), maoto extract (0.9 g/kg/day, ▲; 1.6 g/kg/day, ○) (b), or oseltamivir (2.7 mg/kg/day, ■) from 4 to 52 hours postinfection (c). Asterisks indicate significant difference from mock-infected mice (a) or water-administered mice (b, c) (*; **; ***). Values represent mean ± S.E. ().
