Table 2: Hematological parameters of rats treated orally with PM014 for 13 weeks.

Hematological parametersPM014 (mg/kg/day)
075015003000

Males
 RBC (106/μL)
 HGB (g/dL)
 HCT (%)
 MCV (fL)
 MCH (pg)
 MCHC (g/dL)
 RDW (%)
 HDW (g/dL)
 RET (%)
 PLT (103/μL)
 MPV (fL)
 WBC (103/μL)
 NEU (%)
 LYM (%)
 MONO (%)
 EOS (%)
 BASO (%)
 LUC (%)
 PT (sec)
 APTT (sec)
Females
 RBC (106/μL)
 HGB (g/dL)
 HCT (%)
 MCV (fL)
 MCH (pg)
 MCHC (g/dL)
 RDW (%)
 HDW (g/dL)
 RET (%)
 PLT (103/μL)
 MPV (fL)
 WBC (103/μL)
 NEU (%)
 LYM (%)
 MONO (%)
 EOS (%)
 BASO (%)
 LUC (%)
 PT (sec)
 APTT (sec)

RBC: red blood cell; HGB: haemoglobin concentration; HCT: hematocrit; MCV: mean corpuscular volume; MCH: mean corpuscular hemoglobin; MCHC: mean corpuscular hemoglobin concentration; RDW: red cell distribution width; HDW: Hb concentration distribution width; RET: reticulocytes; PLT: platelet; MPV: mean platelet volume; WBC: white blood cells; NEU: neutrophil; LYM: lymphocyte; MONO: monocyte; EOS: eosinophil; BASO: basophil; LUC: large unstained cells; PT: prothrombin time; APTT: activated partial thromboplastin time. The data shown are the means ± SD ( /group). , compared with the control group.