Akebia trifoliate (Thunb.) Koidz Seed Extract Inhibits the Proliferation of Human Hepatocellular Carcinoma Cell Lines via Inducing Endoplasmic Reticulum Stress

Table 1

List of ER stress-related genes with significant expression in HepG2 cells (fold change ≥1.5-fold).

Probe set ID	Gene symbol	Control	G418	ATSE	1/2(G418 + ATSE)	ATSE/control
8152628	DERL1	199	336	355	694	1.78
7954196	MGST1	733	958	1305	1663	1.78
7995895	HERPUD1	714	1239	1166	2351	1.63
7981335	HSP90AA1	1263	2402	1946	3732	1.54
7956593	OS9	315	357	475	407	1.51
8156838	SEC61B	528	426	348	631	−1.52
8080084	MANF	495	587	320	791	−1.55
8075182	XBP1	758	583	352	343	−2.16

G418 (0.45 mg/mL); ATSE: Akebia trifoliate seed extract (0.625 mg/mL); 1/2(G418 + ATSE): a combination of half dose of each accordingly.