Akebia trifoliate (Thunb.) Koidz Seed Extract Inhibits the Proliferation of Human Hepatocellular Carcinoma Cell Lines via Inducing Endoplasmic Reticulum Stress

Table 4

List of genes with significant expression in the KEGG integrin-mediated cell adhesion pathway for HepG2 cells (fold change ≥1.5-fold).

Probe set ID	Gene symbol	Control	G418	ATSE	1/2(G418 + ATSE)	ATSE/control
7983763	MAPK6	233	314	382	405	1.64
8046380	ITGA6	216	323	385	220	1.78
8051670	SOS1	291	386	520	515	1.79
8084963	PAK2	173	252	360	338	2.08
8090162	ITGB5	330	357	220	150	−1.50
8111915	SEPP1	3337	2847	1761	1131	−1.87

G418 (0.45 mg/mL); ATSE: Akebia trifoliate seed extract (0.625 mg/mL); 1/2(G418 + ATSE): a combination of half dose of each accordingly.