Effects of Angiotensin-Converting Enzyme Inhibitor Derived from Tropaeolum majus L. in Rat Preimplantation Embryos: Evidence for the Dehydroepiandrosterone and Estradiol Role

Table 1

Maternal variables after treatment with HETM (3, 30, and 300 mg/kg) or control (aqueous solution) from the 1st to the 7th day of pregnancy.

Parameters	Experimental groups
	Control	HETM 3	HETM 30	HETM 300
Parturient dams	15	11	13	15
Body weights (g)	261±4.25	259±4.81	265±4.84	258±3.84
Absolute organs weights
Liver (g)	10.9±0.21	9.51±0.27	10.00±0.18	9.77±0.30
Kidneys (g)	0.81±0.01	0.79±0.02	0.78±0.01	0.80±0.02
Adrenals (mg)	19.40±1.18	18.55±1.42	16.69±1.15	18.47±1.18
Ovaries (mg)	27.00±0.93	29.09±2.44	27.08±1.12	27.60±1.36
Uterus (mg)	731.5±44.1	665.9±63.1	707.1±56.2	663.1±44.0
Relative organs weights
Liver (%)	3.86±0.05	3.66±0.09	3.77±0.06	3.78±0.09
Kidneys (%)	0.31±0.01	0.30±0.01	0.29±0.01	0.31±0.01
Adrenals (%)	0.01±0.01	0.01±0.01	0.01±0.01	0.01±0.01
Ovaries (%)	0.01±0.01	0.01±0.01	0.01±0.01	0.01±0.01
Uterus (%)	0.28±0.01	0.25±0.02	0.26±0.02	0.25±0.01

Values are expressed as mean ± S. E. M. using Kruskal-Wallis test followed by Mann-Whitney test.