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Evidence-Based Complementary and Alternative Medicine
Volume 2014, Article ID 217424, 8 pages
http://dx.doi.org/10.1155/2014/217424
Research Article

Effect of Nourishing “Yin”-Removing “Fire” Chinese Herbal Mixture on Hypothalamic NKB/NK3R Expression in Female Precocious Rats

1Department of Neurobiology and Integrative Medicine, Shanghai Medical College, Fudan University, P.O. Box 291, 138 Yi-Xue-Yuan Road, Shanghai 200032, China
2Department of Integrative Medicine, Children’s Hospital, Fudan University, 399 WanYuan Road, Shanghai 200032, China

Received 22 February 2014; Revised 21 May 2014; Accepted 25 May 2014; Published 16 June 2014

Academic Editor: Ping Li

Copyright © 2014 Shiran Wang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. G. Prété, A.-C. Couto-Silva, C. Trivin, and R. Brauner, “Idiopathic central precocious puberty in girls: presentation factors,” BMC Pediatrics, vol. 8, article 27, 2008. View at Publisher · View at Google Scholar · View at Scopus
  2. A. K. Topaloglu, “Neurokinin B signaling in puberty: human and animal studies,” Molecular and Cellular Endocrinology, vol. 324, no. 1-2, pp. 64–69, 2010. View at Publisher · View at Google Scholar · View at Scopus
  3. S. J. Krajewski, M. J. Anderson, L. Iles-Shih, K. J. Chen, H. F. Urbanski, and N. E. Rance, “Morphologic evidence that neurokinin B modulates gonadotropin-releasing hormone secretion via neurokinin 3 receptors in the rat median eminence,” Journal of Comparative Neurology, vol. 489, no. 3, pp. 372–386, 2005. View at Publisher · View at Google Scholar · View at Scopus
  4. J. Young, J. Bouligand, B. Francou et al., “TAC3 and TACR3 defects cause hypothalamic congenital hypogonadotropic hypogonadism in humans,” Journal of Clinical Endocrinology and Metabolism, vol. 95, no. 5, pp. 2287–2295, 2010. View at Publisher · View at Google Scholar · View at Scopus
  5. L. G. Silveira, C. Tusset, and A. C. Latronico, “Impact of mutations in kisspeptin and neurokinin B signaling pathways on human reproduction,” Brain Research, vol. 1364, pp. 72–80, 2010. View at Publisher · View at Google Scholar · View at Scopus
  6. K.-I. Noritake, T. Matsuoka, T. Ohsawa et al., “Involvement of neurokinin receptors in the control of pulsatile luteinizing hormone secretion in rats,” Journal of Reproduction and Development, vol. 57, no. 3, pp. 409–415, 2011. View at Publisher · View at Google Scholar · View at Scopus
  7. V. M. Navarro, J. M. Castellano, S. M. McConkey et al., “Interactions between kisspeptin and neurokinin B in the control of GnRH secretion in the female rat,” The American Journal of Physiology—Endocrinology and Metabolism, vol. 300, no. 1, pp. E202–E210, 2011. View at Publisher · View at Google Scholar · View at Scopus
  8. K. Sakamoto, K. Murata, Y. Wakabayashi et al., “Central administration of neurokinin B activates kisspeptin/NKB neurons in the arcuate nucleus and stimulates luteinizing hormone secretion in ewes during the non-breeding season,” Journal of Reproduction and Development, vol. 58, no. 6, pp. 700–706, 2012. View at Publisher · View at Google Scholar · View at Scopus
  9. V. M. Navarro, “New insights into the control of pulsatile GnRH release: the role of Kiss1/neurokinin B neurons,” Frontiers in Endocrinology, vol. 3, article 48, 2012. View at Publisher · View at Google Scholar · View at Scopus
  10. S. Ramaswamy, S. B. Seminara, B. Ali, P. Ciofi, N. A. Amin, and T. M. Plant, “Neurokinin B stimulates GnRH release in the male monkey (Macaca mulatta) and is colocalized with kisspeptin in the arcuate nucleus,” Endocrinology, vol. 151, no. 9, pp. 4494–4503, 2010. View at Publisher · View at Google Scholar · View at Scopus
  11. Y. Wakabayashi, T. Nakada, K. Murata et al., “Neurokinin B and dynorphin A in kisspeptin neurons of the arcuate nucleus participate in generation of periodic oscillation of neural activity driving pulsatile gonadotropin-releasing hormone secretion in the goat,” Journal of Neuroscience, vol. 30, no. 8, pp. 3124–3132, 2010. View at Publisher · View at Google Scholar · View at Scopus
  12. L. Lazar, R. Kauli, A. Pertzelan, and M. Phillip, “Gonadotropin-suppressive therapy in girls with early and fast puberty affects the pace of puberty but not total pubertal growth or final height,” Journal of Clinical Endocrinology and Metabolism, vol. 87, no. 5, pp. 2090–2094, 2002. View at Publisher · View at Google Scholar · View at Scopus
  13. V. V. Khadilkar, A. V. Khadilkar, and G. B. Maskati, “Growth hormone and GnRHa combination therapy in the management of precocious puberty,” Indian Pediatrics, vol. 42, no. 1, pp. 57–60, 2005. View at Google Scholar · View at Scopus
  14. C. A. Longui, C. Kochi, L. E. P. Calliari et al., “Near-final height in patients with congenital adrenal hyperplasia treated with combined therapy using gh and GnRHa,” Arquivos Brasileiros de Endocrinologia e Metabologia, vol. 55, no. 8, pp. 661–664, 2011. View at Publisher · View at Google Scholar · View at Scopus
  15. J. S. Fuqua, “Treatment and outcomes of precocious puberty: an update,” Journal of Clinical Endocrinology and Metabolism, vol. 98, no. 6, pp. 2198–2207, 2013. View at Publisher · View at Google Scholar · View at Scopus
  16. Z. Tian, H. Zhao, Y. Sun, D. Cai, and B. Chen, “Evaluation of the true precocious puberty rats induced by neonatal administration of Danazol: therapeutic effects of nourishing “Yin”-removing “Fire” Chinese Herb Mixture,” Reproductive Biology and Endocrinology, vol. 3, article 38, 2005. View at Publisher · View at Google Scholar · View at Scopus
  17. D. P. Cai, Z. Y. Ji, and Y. M. Shi, “Clinical study on treatment of female idiopathic precocious puberty with combined therapy of Chinese medicine and megestrol acetate,” Chinese Journal of Integrated Traditional and Western Medicine, vol. 21, no. 10, pp. 732–735, 2001. View at Google Scholar · View at Scopus
  18. Y. Sun, G. N. Perry, J. Yu, B. Chen, and Z. Tian, “Effect of nourishing “Yin”-removing “Fire” Chinese herbal mixture on hypothalamic kisspeptin expression in female precocious rats,” Journal of Ethnopharmacology, vol. 127, no. 2, pp. 274–279, 2010. View at Publisher · View at Google Scholar · View at Scopus
  19. H. Morishita, M. Takemoto, H. Kondo, K. Higuchi, and T. Aono, “Induction of true precocious puberty by neonatal treatment with danazol in female rats,” Neuroscience Letters, vol. 157, no. 1, pp. 33–36, 1993. View at Publisher · View at Google Scholar · View at Scopus
  20. N. E. Rance, “Menopause and the human hypothalamus: evidence for the role of kisspeptin/neurokinin B neurons in the regulation of estrogen negative feedback,” Peptides, vol. 30, no. 1, pp. 111–122, 2009. View at Publisher · View at Google Scholar · View at Scopus
  21. T. L. Dellovade and I. Merchenthaler, “Estrogen regulation of neurokinin B gene expression in the mouse arcuate nucleus is mediated by estrogen receptor α,” Endocrinology, vol. 145, no. 2, pp. 736–742, 2004. View at Publisher · View at Google Scholar · View at Scopus
  22. S. J. Krajewski, M. C. Burke, M. J. Anderson, N. T. Mcmullen, and N. E. Rance, “Forebrain projections of arcuate neurokinin b neurons demonstrated by anterograde tract-tracing and monosodium glutamate lesions in the rat,” Neuroscience, vol. 166, no. 2, pp. 680–697, 2010. View at Publisher · View at Google Scholar · View at Scopus