Research Article

The Effects of Wenxin Keli on Left Ventricular Ejection Fraction and Brain Natriuretic Peptide in Patients with Heart Failure: A Meta-Analysis of Randomized Controlled Trials

Table 1

Characteristics and methodological quality of the included studies.

StudySample size
(T/C)
Diagnosis
standards
ComplicationsInterventionControlTreatment
course
(week)
Clinical
standards
Outcome
measure

Wang et al. 2009 [8]77 (40/37)Diagnostic criteria for CHF (unclear)CHFWXKL 9 g tid + ControlMetoprolol8UnclearLVEF, ADR
Weng 2012 [9]168 (88/80)Diagnostic criteria for CHF (unclear)CHFWXKL 9 g tidConventional therapy
(no detailed information)
8UnclearLVEF
Yu et al. 2006 [10]72 (37/35)Guiding principle of TCM treatment of CHF (1993)CHFWXKL 6 g tidConventional therapy
(no detailed information)
8Guiding principle of clinical research on new drugs of TCM (1993) LVEF
Jia et al. 2011 [11]42 (21/21)Diagnostic criteria for CHF (unclear)CHF and PAFWXKL 9 g tidConventional therapy
(no detailed information)
8UnclearLVEF
Jin 2010 [12]60 (30/30)Diagnostic criteria for CHF (unclear)CHF and VPBWXKL 9 g tidConventional therapy
(no detailed information)
8UnclearLVEF, BNP, ADR
Yue et al. 2012 [13]100 (50/50)Chinese diagnosis and treatment of CHF guidelines (2007)CHF and PAFWXKL 9 g tidConventional therapy
(no detailed information)
8Chinese diagnosis and treatment of CHF guidelines (2007) LVEF, BNP, ADR
Kong et al. 2009 [14]60 (30/30)Diagnostic criteria for CHF (unclear)CHFWXKL 9 g tidConventional therapy
(no detailed information)
8Unclear
guiding
LVEF, BNP
Yang and Dong 2009 [15]80 (40/40)Diagnostic criteria for CHF (unclear) Chinese diagnosisCHFWXKL 9 g tidConventional therapy
(no detailed information)
8Principle of clinical research on new drugs of TCMLVEF, BNP
Hu 2010 [16]98 (50/48)Chinese diagnosis and treatment of CHF guidelines (2007)CHFWXKL 9 g tidConventional therapy
(no detailed information)
8Unclear LVEF, BNP, ADR
Wang 2012 [17]70 (35/35)ACC/AHACHFWXKL 9 g tidConventional therapy
(no detailed information)
8New drug Clinical guidelines (Unclear) LVEF, BNP, ADR
Xu 2012 [18]80 (48/32)Chinese diagnosis and treatment of CHF guidelines (2007)CHFWXKL 9 g tidConventional therapy
(no detailed information)
8UnclearLVEF, BNP