|
First author, publication year,
country,
setting | Treatment duration | Severity; duration of condition | Number of participants randomised/assessed | Age (mean (SD) or range);
gender (M/F) | Intervention* | Control (pharmacotherapy) |
|
Chen et al., 2008 [18],
China,
inpatients | 2 w | NS; I: 9.8 (5.0) y
C: 9.5 (4.6) y | I: 36/36
C: 30/30 | I: 65.7 (8.3); 24/12
C: 64.8 (8.0); 18/12 | Weijing decoction and Er chen decoction | Routine care (oxygen therapy, bronchodilators, antibiotics, mucolytics plus nutritional therapy) not specified |
|
Jing et al., 2007 [9],
China,
inpatients | 1 w | Mild-moderate; I: 17.2 (3.5) y
C: 13.5 (3.7) y | I: 30/30
C: 30/30 | I: 66.3 (5.4); 22/8
C: 67.2 (4.4); 20/10 | Qian jin Weijing decoction | Routine care (bronchodilators, antibiotics, mucolytics plus nutritional therapy) not specified |
|
Liu et al., 2006 [22],
China,
NS | 10 d | I: mild-very severe; 16.86 (10.97) y
C: mild-very severe; 17.20 (11.25) y | I: 30/30
C: 30/30 | I: 69.17 (7.53); 21/9
C: 69.05 (7.83); 22/8 | Jia wei qian jin Weijing decoction | Routine care (oxygen, antibiotics plus nutritional therapy) not specified |
|
Chen and Qiu, 2012 [17],
China,
inpatients | 2 w | I: NS; 16.79 (10.53) y/
C: NS; 17.20 (11.25) y | I: 30/30
C: 30/30 | I: 72.07 (8.39); 20/10
C: 71.05 (7.93); 22/8 | Qian jin Weijing decoction | Oxygen therapy, Methylxanthines (Doxofylline 0.3 g iv qd); Ventolin 2 spray inhaled, Ipratropium 10 mL qd inhaled, Levofloxacin, 0.4 g, IV, qd; ambroxol hydrochloride, 30 mg, IV, tid; |
|
Shi et al., 2007 [24],
China,
inpatients | 2 w | I: mild: 4, moderate: 29, severe: 7, 16.34 (9.53) y/
C: mild: 2, moderate: 19, severe: 9; 17.17 (10.22) y | I: 40/40
C: 30/30 | I: 61.4 (6.8); 27/13
C: 59.5 (7.2); 18/12 | Weijing xuan bi decoction | Oxygen therapy, antibiotics (Cefmetazole 1 g iv bid) plus methylxanthines (Aminophylline 0.1 g, bid) plus mucolytic (Mucosolvan 30 mg bid) |
|
Zhang et al., 2009 [28],
China,
inpatients | 10 d | NS | I: 30/30
C: 30/30 | I: 65.21 (6.02); 25/5
C: 65.30 (6.13); 23/7 | Qian jin Weijing decoction | Oxygen therapy, antibiotics plus methylxanthines (Theophylline 0.2 g, bid) plus mucolytic (Mucosolvan 30 mg tid) |
|
Chen and Wang, 2009 [19],
China,
inpatients | 15 d | NS | I: 31/31
C: 31/31 | I: 62.5 (NS); 23/8
C: 61.7 (NS); 22/9 | Weijing decoction | Oxygen therapy, Cefalexin, 3 g, qd-bid; ipratropium, 2 mL, inhaled, tid; salbutamol, 1 mL, inhaled, tid; theophylline, 0.2 g, bid; Mucosolvan, 30 mg, tid |
|
Li, 2009 [10],
China,
inpatients | 10 d | I: mild: 5, moderate: 25; 9.94 (3.62) y/
C: mild: 6, moderate: 24; 8.98 (3.41) y | I: 30/30
C: 30/30 | I: 63.87 (8.64); 19/11
C: 63.62 (7.23); 18/12 | Qian jin Weijing decoction | oxygen therapy, Levofloxacin, 0.3 g, IV, qd; salbutamol, 200 ug, inhaled tid, ipratropium, 20 ug, inhaled, tid, theophylline, 0.2 g, PO, bid; ambroxol hydrochloride, 30 mL, tid |
|
Shi et al., 2010 [23],
China,
NS | 10 d | NS | I: 20/20
C: 20/20 | Total: 52–83; 31/9 | Weijing decoction and liu jun zi decoction | Routine care (oxygen therapy, bronchodilators, antibiotics, mucolytics, and others) not specified |
|
Jing et al., 2006 [21],
China,
inpatients | 10 d | mild-moderate; I: 13.2 (3.7) y
C: 12.8 (3.9) y | I: 30/30
C: 30/30 | I: 64.7 (5.2); 21/9
C: 64.2 (4.9); 18/12 | Qian jin Weijing decoction jia jian | Routine care (bronchodilators, antibiotics, mucolytics plus nutritional therapy) not specified |
|
Xu, 2012 [25],
China,
out/inpatients | 2 w | I: NS; 12.24 (3.79) y/
C: NS; 15.29 (5.34) y | I: 40/40
C: 38/38 | I: 65.82 (11.73); 23/17
C: 64.15 (13.84); 21/17 | Qian jin Weijing decoction and ma xing shi gan decoction | Oxygen therapy, antibiotics plus methylxanthines (Aminophylline) plus mucolytic (Mucosolvan) |
|
Zang, 2010 [26],
China,
inpatients | 2 w | Mild-severe; I: 11.6 (NS) d
C: 10.4 (NS) d | I: 35/35
C: 35/35 | I: 62.3 (NS); 23/12
C: 61.7 (NS); 24/11 | Qian jin Weijing decoction and ma xing shi gan decoction | Routine care (bronchodilators, antibiotics, mucolytics plus nutritional therapy) not specified |
|
Zhang, 2011 [29],
China,
NS | 10 d | NS | I: 40/40
C: 40/40 | Total: 67.7 (7.1); 59/21 | Qian jin Weijing decoction (modified) | Routine care (oxygen therapy, bronchodilators, antibiotics, mucolytics) not specified |
|
Zhan, 2008 [27],
China,
out/inpatients | 10 d | I: mild: 5, moderate: 13, severe: 12; 15.46 (8.37) y/
C: mild: 5, moderate: 15, severe: 10; 16.01 (2.68) y | I: 30/30
C: 30/30 | I: 65.7 (8.54); 25/5
C: 64.9 (9.61); 23/7 | Weijing decoction | Oxygen therapy, Levofloxacin, 0.3 g, IV, qd methylxanthines (Aminophylline 0.1 g, bid) plus mucolytic (ambroxol, 30 mg, tid) |
|
Guo, 2010 [20],
China,
inpatients | 15 d | I: NS; 8.9 y
C: NS; 9.3 y | I: 56/56
C: 44/44 | I: 63.5; 30/26
C: 68.5; 21/23 | Weijing decoction | Oxygen therapy, antibiotics plus methylxanthines (Theophylline 0.2 g, bid) plus mucolytic (Mucosolvan 30 mg tid) |
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