Fenugreek Prevents the Development of STZ-Induced Diabetic Nephropathy in a Rat Model of Diabetes
Figure 4
Fenugreek suppressed the mRNA and protein expressions of TGF-β1 in diabetic kidney. MRNA and protein levels of TGF-β1 (a and b) were tested by qPCR and western blot assay, respectively. Beta-actin was used as the internal standard in each sample. Data for relative quantity of TGF-β1 mRNA and protein were conducted by densitometric analysis. At the same time, histopathological examinations were performed by immunohistochemistry (c). They suggested the same results. versus Con; versus DN.