Fenugreek Prevents the Development of STZ-Induced Diabetic Nephropathy in a Rat Model of Diabetes

Table 1

Decreased blood glucose and alleviated renal dysfunctions after fenugreek treatment.

	Con	DN	DF
Glucose (mmol/L)	6.12±1.56	18.09±4.1^∗	7.42±2.68^#
Albuminuria (mg/day)	7.28±3.24	17.23±3.26^∗	10.13±3.03^#
HbAlc (%)	6.39±1.52	12.95±4.36^∗	8.12±1.38^#
DMF (mmol/L)	1.82±0.39	2.93±0.68^∗	2.05±0.41^#
BUN (mmol/L)	6.59±1.43	17.82±3.01^∗	9.14±1.59^#
Scr (𝜇mol/L)	25.90±2.83	51.91±5.69^∗	25.34±2.61^#
KI (g/g)	2.72±0.61	5.94±0.51^∗	4.69±0.41^#

Twelve weeks after fenugreek treatment, renal function parameters of the nondiabetic control group (Con), STZ-induced diabetic group (DN), and the fenugreek-treated diabetic group (DF) were tested. Data are presented as mean ± SD from 10 animals (𝑛=10) for each group. The kidney index (KI) was calculated as 1000 × kidney weight/body weight. ^∗𝑃<0.05 versus Con; ^#𝑃<0.05 versus DN.