The Anxiolytic Effects of Valtrate in Rats Involves Changes of Corticosterone Levels

Figure 6

Behavioural performance of rat registered in a 5 min session in the EPM performed 1 h after the administration of vehicle (p.o.), valtrate (5, 10, and 20 mg/kg, p.o.), and 0.5 h after the administration of diazepam (1 mg/kg, p.o.). (a) Percentage of number of entries into the open arm, (b) percentage of time spent into the open arms, and (c) total arm entries. Columns represent the means ± SEM, 𝑛=12 rats. *𝑃<0.05, **𝑃<0.01 compared to the vehicle group.

(a)

(b)

(c)