Danggui-Shaoyao-San Improves Learning and Memory in Female SAMP8 via Modulation of Estradiol

Table 3

Effects of DSS on the latency during the training trial sessions for female SAMP8.

Day	Escape latency (s)
	SAMR1	SAMP8	SAMP8 + DSS (g/kg)
			1.6	3.2	4.8
1	26.57±4.35	𝟑𝟗.𝟔𝟔±𝟒.𝟏𝟗^∗	33.70±3.68	33.90±3.17	37.36±3.32
2	20.62±3.80	𝟒𝟓.𝟔𝟏±𝟒.𝟖𝟒^∗∗	𝟐𝟗.𝟗𝟔±𝟒.𝟒𝟏^#	𝟐𝟗.𝟗𝟗±𝟒.𝟎𝟔^#	𝟐𝟓.𝟕𝟎±𝟓.𝟏𝟏^#
3	19.25±4.03	𝟒𝟑.𝟕𝟑±𝟒.𝟏𝟕^∗∗	𝟑𝟎.𝟑𝟐±𝟑.𝟒𝟏^#	𝟐𝟒.𝟑𝟗±𝟑.𝟖𝟖^##	𝟐𝟔.𝟔𝟎±𝟓.𝟕𝟔^##
4	11.95±2.45	𝟑𝟕.𝟖𝟑±𝟔.𝟏𝟕^∗∗	35.55±4.61	27.86±4.38	22.35±4.84
5	10.04±1.48	𝟑𝟔.𝟎𝟐±𝟔.𝟑𝟕^∗∗	26.67±4.01	21.84±2.13	22.67±5.63
6	8.06±1.14	𝟑𝟖.𝟏𝟎±𝟔.𝟒𝟒^∗∗	𝟐𝟏.𝟎𝟎±𝟑.𝟓𝟐^#	𝟏𝟖.𝟔𝟏±𝟐.𝟓𝟕^#	𝟏𝟗.𝟕𝟓±𝟑.𝟔𝟕^#

^∗𝑃<0.05, ^∗∗𝑃<0.01, compared with SAMR1; ^#𝑃<0.05. ^##𝑃<0.01 compared with SAMP8. Data values are expressed as mean ± SEM, 𝑛=9-10.