Effects of Anethole in Nociception Experimental Models

Table 1

Reaction time of animals in hot plate test: 0, 15, 30, 60, and 90 min after treatment of anethole (62.5, 125, 250, and 500 mg/kg, p.o.) and meperidine (50 mg/kg, i.p.).

Treatment; (mg/kg)	Reaction time (s)
	0 min	15 min	30 min	60 min	90 min
Control
Anethole 62.5
Anethole 125
Anethole 250
Anethole 500
Meperidine

Control: animals that received oral treatment of saline (10 mg/kg): Anethole 62.5, 125, 250, and 500: animals that received oral treatment of anethole in doses of 62.5, 125, 250, and 500 mg/kg, respectively; meperidine: animals that received intraperitoneal injection of meperidine in doses of 50 mg/kg. Data are represented as mean ± S.E.M. , compared with the control group (one-way ANOVA followed by Tukey test).