Subacute Oral Toxicity of Yukmijiwhang-Tang in Crl:CD Sprague-Dawley Rats and Its Cytotoxicity

Table 9

Cytotoxicity of YMJ against various cell lines.

Cell line	Origin	Concentration (μg/mL)
		0	10	20	50	100	200
SH-SY5Y	Human, neuroblastoma	100 ± 1.84	97 ± 1.69	98 ± 0.92	96 ± 1.17	100 ± 2.40	101 ± 0.60
Clone M-3	Mouse, melanoma	100 ± 9.99	95 ± 5.17	95 ± 3.66	94 ± 4.67	94 ± 2.34	94 ± 1.40
SK-N-SH	Human, neuroblastoma (brain)	100 ± 4.14	101 ± 0.78	93 ± 4.01	102 ± 1.35	98 ± 1.70	98 ± 4.53
U-373 MG	Human, glioblastoma (brain)	100 ± 8.15	96 ± 8.06	97 ± 4.48	96 ± 8.70	95 ± 5.41	94 ± 6.69
U-87 MG	Human, glioblastoma (brain)	100 ± 3.03	97 ± 5.65	95 ± 3.67	95 ± 4.6	99 ± 5.39	97 ± 4.74
HEK-293	Human, kidney	100 ± 6.96	124 ± 3.74	126 ± 3.55	118 ± 2.11	117 ± 3.96	118 ± 2.37
HepG2	Human, hepatoblastoma	100 ± 3.40	95 ± 4.11	94 ± 4.42	92 ± 4.47	91 ± 4.44	90 ± 2.09
Hep3B	Human, hepatocarcinoma	100 ± 2.73	101 ± 1.43	100 ± 2.79	99 ± 3.13	97 ± 1.61	92 ± 0.86
RAW264.7	Mouse, macrophage	100 ± 2.15	107 ± 1.90	110 ± 2.02	109 ± 4.06	108 ± 6.42	108 ± 3.17
3T3-L1	Mouse, fibroblast (preadipocyte)	100 ± 1.68	101 ± 0.47	97 ± 1.58	98 ± 2.32	101 ± 3.11	92 ± 3.91
HIT-T15	Hamster, pancreas	100 ± 0.60	101 ± 2.10	100 ± 3.40	99 ± 2.50	98 ± 3.10	100 ± 2.30
HL-60	Human, leukemia, lymphoblast	100 ± 2.56	99 ± 3.30	100 ± 2.43	98 ± 1.82	99 ± 2.73	99 ± 2.61
HT-29	Human, colon cancer cell	100 ± 4.28	107 ± 7.36	104 ± 6.67	107 ± 14.16	105 ± 13.91	97 ± 4.00
NIH3T3	Mouse, fibroblast	100 ± 7.56	102 ± 9.10	101 ± 2.39	101 ± 1.93	101 ± 3.94	101 ± 8.42
B16F10	Mouse, melanoma	100 ± 6.86	101 ± 8.66	93 ± 6.32	102 ± 4.23	98 ± 4.84	98 ± 6.26
MCF-7	Human, breast cancer	100 ± 1.66	103 ± 2.45	105 ± 1.95	113 ± 3.67	114 ± 2.12	114 ± 1.47
HaCaT	Human, keratinocyte	100 ± 2.69	96 ± 2.08	90 ± 4.12	91 ± 3.59	89 ± 2.87	89 ± 2.90
PC12	Rat, adrenal medulla, pheochromocytoma	100 ± 2.92	109 ± 2.01	105 ± 0.42	105 ± 2.05	103 ± 1.19	106 ± 2.71
AGS	Human, gastric adenocarcinoma	100 ± 0.74	101 ± 0.92	94 ± 0.51	100 ± 0.80	95 ± 1.76	95 ± 0.79
BEAS-2B	Human, bronchial epithelial, normal cell	100 ± 5.09	102 ± 2.64	107 ± 4.50	93 ± 3.78	96 ± 1.54	88 ± 2.27
LNCaP	Human, prostate cancer	100 ± 8.39	106 ± 6.33	106 ± 6.92	104 ± 10.50	103 ± 10.95	105 ± 8.63
RBL-1	Rat, basophilic leukemia	100 ± 2.55	98 ± 2.89	94 ± 0.75	94 ± 1.39	94 ± 1.71	94 ± 0.88
NRK52	Rat, kidney	100 ± 1.96	122 ± 2.27	121 ± 2.96	121 ± 0.95	124 ± 1.55	123 ± 2.34