Ligand-Based and Structure-Based Investigation for Alzheimer’s Disease from Traditional Chinese Medicine

Table 3

Radius of gyration (Rg) calculated for the control and TCM candidates.

	Radius of gyration (Rg; nm)
	Tacrolimus		Daphnetoxin		20-O-(2′E,4′E-Decadienoyl)ingenol		Lythrancine II
	Average	Maximum	Average	Maximum	Average	Maximum	Average	Maximum
Protein	2.154	2.210	2.179	2.219	2.178	2.237	2.157	2.200
Mainchain	2.140	2.202	2.162	2.205	2.165	2.226	2.142	2.187
Sidechain	2.167	2.216	2.160	2.202	2.190	2.247	2.170	2.212
Backbone	2.137	2.200	2.160	2.202	2.163	2.223	2.140	2.185
C alpha	2.141	2.204	2.165	2.207	2.167	2.227	2.144	2.189
Ligand	0.541	0.575	0.378	0.384	0.570	0.558	0.394	0.413