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Evidence-Based Complementary and Alternative Medicine
Volume 2014, Article ID 365258, 9 pages
http://dx.doi.org/10.1155/2014/365258
Research Article

Immunosuppressive Effects of A-Type Procyanidin Oligomers from Cinnamomum tamala

School of Pharmacy, Shanghai University of Traditional Chinese Medicine (SHUTCM), Shanghai 201203, China

Received 10 July 2014; Revised 13 September 2014; Accepted 16 September 2014; Published 30 October 2014

Academic Editor: Youn C. Kim

Copyright © 2014 Liang Chen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. J. D. Keys, Chinese Herbs: Their Botany Chemistry and Pharmacodynamics, Tuttle Publishing, Rutland, Vt, USA, 1976.
  2. W. Fan, “Efficacy observation on treating 62 cases of rheumatoid arthritis in the Xin-Du-Huo-Tang Decoction,” Shanxi Journal of Traditional Chinese Medicine, vol. 17, no. 1, p. 20, 2001. View at Google Scholar
  3. F. Qin, “Clinical observation of therapeutic effect of Er-xian-yi-shen Decoction in treating rheumatoid arthritis,” Modern Medicine & Health, vol. 25, no. 10, pp. 1481–1482, 2009. View at Google Scholar
  4. X. Xiong, “Clinical experience in treating rheumatoid arthritis by ‘Wendu Tongbi Decoction’,” Shanghai Journal of Traditional Chinese Medicine, vol. 44, no. 8, pp. 54–55, 2010. View at Google Scholar
  5. W. Tang and G. Eisenbrand, Chinese Drugs of Plant Origin: Chemistry, Pharmacology, and Use in Traditional and Modern Medicine, Springer, Berlin, Germany, 1992.
  6. M. Kubo, S. Ma, J. Wu, and H. Matsuda, “Anti-inflammatory activities of 70% methanolic extract from cinnamomi cortex,” Biological and Pharmaceutical Bulletin, vol. 19, no. 8, pp. 1041–1045, 1996. View at Publisher · View at Google Scholar · View at Scopus
  7. B.-J. Lee, Y.-J. Kim, D.-H. Cho, N.-W. Sohn, and H. Kang, “Immunomodulatory effect of water extract of cinnamon on anti-CD3-induced cytokine responses and p38, JNK, ERK1/2, and STAT4 activation,” Immunopharmacology and Immunotoxicology, vol. 33, no. 4, pp. 714–722, 2011. View at Publisher · View at Google Scholar · View at Scopus
  8. H. Cao, J. F. Urban Jr., and R. A. Anderson, “Cinnamon polyphenol extract affects immune responses by regulating anti- and proinflammatory and glucose transporter gene expression in mouse macrophages,” Journal of Nutrition, vol. 138, no. 5, pp. 833–840, 2008. View at Google Scholar · View at Scopus
  9. V. Sachin, L. B. Subhash, M. Vishwaraman, and A. T. Prasad, “Anti-inflammatory and anti-arthritic activity of type-A procyanidine polyphenols from bark of Cinnamomum zeylanicum in rats,” Food Science and Human Wellness, vol. 2, no. 2, pp. 59–67, 2013. View at Publisher · View at Google Scholar
  10. S. Morimoto, G.-I. Nonaka, and I. Nishioka, “Tannins and related compounds. XXXIX.: procyanidin C-glucosides and an acylated flavan-3-ol glucoside from the barks of Cinnamomum cassia BLUME and C. obtusifolium NEES,” Chemical and Pharmaceutical Bulletin, vol. 34, no. 2, pp. 643–649, 1986. View at Publisher · View at Google Scholar · View at Scopus
  11. G. I. Nonaka, S. Morimoto, and I. Nishioka, “Tannins and related compounds. Part 13. Isolation and structures of trimeric, tetrameric, and pentameric proanthicyanidins from cinnamon,” Journal of the Chemical Society, Perkin Transactions 1, pp. 2139–2145, 1983. View at Google Scholar · View at Scopus
  12. Z. L. Lu, Q. Jia, R. Wang et al., “Hypoglycemic activities of A- and B-type procyanidin oligomer-rich extracts from different Cinnamon barks,” Phytomedicine, vol. 18, no. 4, pp. 298–302, 2011. View at Publisher · View at Google Scholar · View at Scopus
  13. L. Chen, P. Sun, T. Wang et al., “Diverse mechanisms of antidiabetic effects of the different procyanidin oligomer types of two different cinnamon species on db/db mice,” Journal of Agricultural and Food Chemistry, vol. 60, no. 36, pp. 9144–9150, 2012. View at Publisher · View at Google Scholar · View at Scopus
  14. Y.-H. Feng, Y.-N. Zhu, J. Liu et al., “Differential regulation of resveratrol on lipopolysacchride-stimulated human macrophages with or without IFN-γ pre-priming,” International Immunopharmacology, vol. 4, no. 6, pp. 713–720, 2004. View at Publisher · View at Google Scholar · View at Scopus
  15. R. Zhou, F. Zhang, P.-L. He et al., “(5R)-5-hydroxytriptolide (LLDT-8), a novel triptolide analog mediates immunosuppressive effects in vitro and in vivo,” International Immunopharmacology, vol. 5, no. 13-14, pp. 1895–1903, 2005. View at Publisher · View at Google Scholar · View at Scopus
  16. A. M. Balde, T. de Bruyne, L. Pieters et al., “Oligomeric proanthocyanidins possessing a doubly linked structure from Pavetta owariensis,” Phytochemistry, vol. 38, no. 3, pp. 719–723, 1995. View at Publisher · View at Google Scholar · View at Scopus
  17. L. Liu, B. Xie, S. Cao, E. Yang, X. Xu, and S. Guo, “A-type procyanidins from Litchi chinensis pericarp with antioxidant activity,” Food Chemistry, vol. 105, no. 4, pp. 1446–1451, 2007. View at Publisher · View at Google Scholar · View at Scopus
  18. G. K. Jayaprakasha, M. Ohnishi-Kameyama, H. Ono, M. Yoshida, and L. J. Rao, “Phenolic constituents in the fruits of Cinnamomum zeylanicum and their antioxidant activity,” Journal of Agricultural and Food Chemistry, vol. 54, no. 5, pp. 1672–1679, 2006. View at Publisher · View at Google Scholar · View at Scopus
  19. K. B. Killday, M. H. Davey, J. A. Glinski et al., “Bioactive A-type proanthocyanidins from Cinnamomum cassia,” Journal of Natural Products, vol. 74, no. 9, pp. 1833–1841, 2011. View at Publisher · View at Google Scholar · View at Scopus
  20. H. C. Lin and S. S. Lee, “Proanthocyanidins from the leaves of Machilus philippinensis,” Journal of Natural Products, vol. 73, no. 8, pp. 1375–1380, 2010. View at Publisher · View at Google Scholar · View at Scopus
  21. K. Kamiya, C. Watanabe, H. Endang, M. Umar, and T. Satake, “Studies on the constituents of bark of Parameria laevigata Moldenke,” Chemical and Pharmaceutical Bulletin, vol. 49, no. 5, pp. 551–557, 2001. View at Publisher · View at Google Scholar · View at Scopus
  22. A. Balde, T. de Bruyne, L. Pieters et al., “Tetrameric proanthocyanidins containing a double interflavanoid (A-type) linkage from Pavetta owariensis,” Phytochemistry, vol. 40, no. 3, pp. 933–938, 1995. View at Publisher · View at Google Scholar · View at Scopus
  23. Y. Moumou, F. Trotin, J. Vasseur et al., “Procyanidin production by Fagopyrum esculentum callus culture,” Planta Medica, vol. 58, no. 6, pp. 516–519, 1992. View at Publisher · View at Google Scholar · View at Scopus
  24. L. Y. Foo and J. J. Karchesy, “Procyanidin dimers and trimers from Douglas fir inner bark,” Phytochemistry, vol. 28, no. 6, pp. 1743–1747, 1989. View at Publisher · View at Google Scholar · View at Scopus
  25. M. Hör, M. Heinrich, and H. Rimpler, “Proanthocyanidin polymers with antisecretory activity and proanthocyanidin oligomers from Guazuma ulmifolia bark,” Phytochemistry, vol. 42, no. 1, pp. 109–119, 1996. View at Publisher · View at Google Scholar · View at Scopus
  26. N. Hill and N. Sarvetnick, “Cytokines: promoters and dampeners of autoimmunity,” Current Opinion in Immunology, vol. 14, no. 6, pp. 791–797, 2002. View at Publisher · View at Google Scholar · View at Scopus
  27. E. T. Andreakos, B. M. Foxwell, F. M. Brennan, R. N. Maini, and M. Feldmann, “Cytokines and anti-cytokine biologicals in autoimmunity: present and future,” Cytokine and Growth Factor Reviews, vol. 13, no. 4-5, pp. 299–313, 2002. View at Publisher · View at Google Scholar · View at Scopus
  28. S. Grabbe and T. Schwarz, “Immunoregulatory mechanisms involved in elicitation of allergic contact hypersensitivity,” Immunology Today, vol. 19, no. 1, pp. 37–44, 1998. View at Publisher · View at Google Scholar · View at Scopus
  29. K. Kobayashi, K. Kaneda, and T. Kasama, “Immunopathogenesis of delayed-type hypersensitivity,” Microscopy Research and Technique, vol. 53, no. 4, pp. 241–245, 2001. View at Publisher · View at Google Scholar · View at Scopus