Inhibitory Effect of a Hot-Water Extract of Leaves of Japanese Big-Leaf Magnolia (Magnolia obovata) on Rotavirus-Induced Diarrhea in Mouse Pups

Figure 5

Effect of fractionated MLE on CPE in SA11-infected MA104 cells. MA104 cells were treated with fractionated MLE 1 h after the exposure to SA11 strain. The cells were cultured for another 72 h and subjected to neutral red uptake assay to measure CPE produced by SA11 infection. (a) Effects of hexane-soluble and hexane-insoluble MLE fraction on cytopathic injury. Data are presented as relative mean value ± SD against fraction-untreated control (). versus fraction-untreated control. (b) Effects of the 70% MeOH-soluble and 70% MeOH-insoluble fractions on cytopathic injury. Data are presented as relative mean value ± SD against the fraction-untreated control (). and versus fraction-untreated control. (c) Effects of water-soluble and 1-BuOH-soluble MLE fractions on cytopathic injury. Data are presented as relative mean value ± SD against the fraction-untreated control (). versus fraction-untreated control.

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