Protection of Tong-Sai-Mai Decoction against Apoptosis Induced by H₂O₂ in PC12 Cells: Mechanisms via Bcl-2-Mitochondria-ROS-INOS Pathway

Figure 1

(a) The protective effect of TSM on the cell viability in H₂O₂-treated PC12 cells. The cells were treated with 200 μmol/L H₂O₂ and 0.05, 0.5, and 5 mg/mL TSM with 200 μmol/L H₂O₂. The values given are the mean ± SEM (). and as compared with the control group; and as compared with the H₂O₂ group. (b) The effects of cell viability of H₂O₂ and H₂O₂ + 5 mg/mL TSM treated PC12 cells and HUVEC cells. The cells were treated with 200 μmol/L H₂O₂ and (200 μmol/L H₂O₂ + 5 mg/mL TSM) in the PC12 cells and HUVEC cells. The values given are the mean ± SEM (). as compared with the control group.

(a)

(b)