Protection of Tong-Sai-Mai Decoction against Apoptosis Induced by H₂O₂ in PC12 Cells: Mechanisms via Bcl-2-Mitochondria-ROS-INOS Pathway

Figure 12

Influence of different treatments of TSM concentrations on the expression of INOS in PC12 cells. The rate of INOS expression was tested by FCM assay. (a) Control group. The cells were treated with 200 μmol/L H₂O₂ (b) and 0.05, 0.5, and 5 mg/mL TSM in the presence of 200 μmol/L H₂O₂ ((c), (d), and (e)). TSM could inhibit overexpression of INOS induced by 200 μmol/L H₂O₂ (TSM + H₂O₂). and as compared with the control group; and as compared with the H₂O₂ group.

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