Protection of Tong-Sai-Mai Decoction against Apoptosis Induced by H₂O₂ in PC12 Cells: Mechanisms via Bcl-2-Mitochondria-ROS-INOS Pathway

Figure 7

The cell cycle modifications induced by TSM. (a) Control group. The cells were treated with 200 μmol/L H₂O₂ (b) and 0.05, 0.5, and 5 mg/mL TSM in the presence of 200 μmol/L H₂O₂ ((c), (d), and (e)). The blue color represented the diploid G1 phase; the red color represented the diploid G2 phase; and the grey color represented the diploid S phase. The percentage of G1, G2, and S in cells treated with 200 μmol/L H₂O₂ and various concentrations of TSM and cumulative data from three independent experiments were shown.

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(b)

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(e)

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