Evaluation of Blueberry Juice in Mouse Azoxymethane-Induced Aberrant Crypts and Oxidative Damage
Table 2
Aberrant crypts in mice treated with blueberry juice (BJ) and azoxymethane (AOM).
Group
Number of aberrant crypts
Mean ± SD
1
2
3
4
5
6
7
Water 15 μL/g
0
0
0
0
0
0
0
0
AOM 10 mg/kg
57.14 ± 6.85
10 ± 1.44
3.28 ± 0.77
1.85 ± 0.41
0.14 ± 0.14
0.42 ± 0.42
0.42 ± 0.20
73.25 ± 1.44a
BJ 15 μL/g
1.71 ± 0.89
0.28 ± 0.18
0
0
0
0
0
1.99 ± 0.54
BJ + AOM 1.6 μL/g + 10 mg/kg
23.17 ± 3.37
1.83 ± 0.71
0.66 ± 0.49
0.16 ± 0.17
0
0
0
25.82 ± 1.19a,b
BJ + AOM 4.1 μL/g + 10 mg/kg
8.5 ± 1.65
0.75 ± 0.37
0.37 ± 0.26
0.12 ± 0.13
0
0.12 ± 0.13
0
9.86 ± 0.51a,b
BJ + AOM 15 μL/g + 10 mg/kg
299.5 ± 43.14
12 ± 2.72
4.16 ± 1.09
1 ± 0.26
0.33 ± 0.21
0
0
316.99 ± 9.48a,b
Values represent the mean ± SD obtained in the colon of 8 mice per group. aStatistically significant with respect to the mean control value and bwith respect to the value of the AOM treated group. ANOVA and Student-Newman-Keuls tests, .
