Protective Effect of Repeatedly Preadministered Brazilian Propolis Ethanol Extract against Stress-Induced Gastric Mucosal Lesions in Rats
Figure 1
Effects of repeated or a single BPEE preadministration and a single VE preadministration on gastric mucosal lesion development in rats with WIRS. Fasted rats receiving BPEE (50 mg/kg), VE (250 mg/kg) or vehicle at 30 min before the onset of WIRS or BPEE (50 mg/kg) at the same time point after its preadministration for successive six days were exposed to WIRS for 6 h at 23°C as described in Section 2. S and R in the parentheses represent a single manner and a repeated manner of BPEE preadministration, respectively. The lesion index of gastric mucosal tissues was determined as described in Section 2. Each value is a mean ± S.D. ( for each group). (versus rats with WIRS alone).
