Influence of First-Line Antibiotics on the Antibacterial Activities of Acetone Stem Bark Extract of Acacia mearnsii De Wild. against Drug-Resistant Bacterial Isolates

Table 2

Antibacterial effects of acetone stem bark extract of A. mearnsii and the different first-line antibiotics.

Tested bacterial isolates	Minimum inhibitory concentrations (MIC)
	AMA	Ery	Tet	Met	Amx	Cip	Nal	Chl	Kan
	mg/mL	µg/mL
Escherichia  coli ATCC 25922	0.625	0.391R	0.976S	31.250R	3.906S	0.039S	1.953S	3.906S	125R
Bacillus  cereus ATCC 10702	0.156	0.098S	0.244S	31.250R	7.813R	0.078S	15.625S	3.906S	125R
Pseudomonas  aeruginosa ATCC 19582	0.156	0.195S	0.488S	15.625R	3.906S	0.156S	7.813S	3.906S	31.25R
Serratia  marcescens ATCC 9986	0.625	3.125R	15.625R	31.250R	31.25R	0.078S	1.953S	0.977S	1.953S
Enterococcus  faecalis KZN	0.625	12.500R	15.625R	62.500R	0.977S	0.313S	62.500R	31.250R	500R
Staphylococcus  aureus OK1	0.078	0.195S	0.976S	15.625R	0.977S	0.078S	62.500R	7.813R	15.625R
Salmonella  typhi ATCC 13311	0.313	6.250R	0.244S	31.250R	0.977S	0.0195S	7.813S	3.906S	15.625R
Micrococcus  luteus	0.039	0.391R	31.250R	31.250R	0.488S	1.250R	62.500R	1.953S	250R
Proteus  vulgaris CSIR 0030	0.156	0.048S	0.488S	62.500R	0.244S	0.0195S	62.500R	31.250R	31.25R
Shigella  flexneri KZN	0.078	0.195S	0.488S	62.500R	250.000R	0.039S	62.500R	7.813	15.625R

S: sensitive; R: resistant; AMA: acetone extract of A. mearnsii; Ery: erythromycin; Tet: tetracycline; Met: metronidazole; Cip: ciprofloxacin; Nal: nalidixic acid; Chl: chloramphenicol; Kan: kanamycin.