Mechanisms Underlying the Antinociceptive, Antiedematogenic, and Anti-Inflammatory Activity of the Main Flavonoid from Kalanchoe pinnata

Figure 1

Effect of KPFE (a) and KPFV (b) on the acetic acid-induced abdominal writhing test. KPFE, KPFV, or indomethacin (Indo) was subcutaneously administrated 30 min before acetic acid injection (1.2%, 0.1 mL/10 g). The number of acetic acid-induced abdominal writhings was counted for the following 30 min. , , and significantly different from the vehicle-treated group. Values represent the mean ± SEM of 5-6 mice.

(a)

(b)