Electrical Stimulation at the ST36 Acupoint Protects against Sepsis Lethality and Reduces Serum TNF Levels through Vagus Nerve- and Catecholamine-Dependent Mechanisms
Figure 3
Effects of electroacupuncture on survival rates in a rat model of sepsis and organ injury induced by CLP. Four groups of rats () were formed: one group underwent surgery without CLP (SHAM), and three groups were subjected to CLP, where one of these groups was treated with EA at ST36 (CLP+ST36) or SHAM acupuncture (CLP+SHAM-EA) after closure and suturing of the abdominal cavity. The percentage survival at 72 hours after surgery is shown. Differences in the survival curve were evaluated using the Mantel-Cox test. Significant differences are indicated with an asterisk: . The data are representative of two independent experiments. (b) In independent assay, livers, kidneys, and lungs were harvested 18 h after CLP for histopathologic examination using hematoxylin and eosin staining. Representative images from six animals per group were shown. Original magnification: ×400.
