Immunomodulatory and Antidiabetic Effects of a New Herbal Preparation (HemoHIM) on Streptozotocin-Induced Diabetic Mice

<table>ICR mice orally administrated HemoHIM (4 weeks) before being injected with STZ. Effect of HemoHIM administration on plasma (a) and pancreatic <i>β</i>-cell ((b), ×200) insulin levels in STZ-induced diabetic mice.Pancreas was immunohistochemically stained as described in Materials and Methods. Values are expressed as means ± S.D. <svg height="17.825001" id="M10" style="vertical-align:-3.13504pt" version="1.1" viewbox="0 0 69.150002 17.825001" width="69.150002" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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q0 -76 10 -138.5t37 -107.5t69 -45q32 0 55.5 25t35.5 68.5t17.5 91.5t5.5 105t-5.5 105.5t-18 92t-36 68t-56.5 24.5z" id="x30"></path></g><g transform="matrix(.017,-0,0,-.017,60.919,13.688)"><path d="M153 550l-26 -186q79 31 111 31q90 0 141.5 -51t51.5 -119q0 -93 -89 -166q-85 -69 -173 -71q-32 0 -61.5 11.5t-41.5 23.5q-18 17 -17 34q2 16 22 33q14 9 26 -1q61 -50 124 -50q60 0 93 43.5t33 104.5q0 69 -41.5 110t-121.5 41q-53 0 -102 -20l38 305h286l6 -8
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</svg> compared with nondiabetic group. <svg height="19.65" id="M11" style="vertical-align:-3.13504pt" version="1.1" viewbox="0 0 70.224998 19.65" width="70.224998" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> compared with diabetic group.</table>

Evidence-Based Complementary and Alternative Medicine

fig3

Figure 3

Figure 3: Immunomodulatory and Antidiabetic Effects of a New Herbal Preparation (HemoHIM) on Streptozotocin-Induced Diabetic Mice 