Antileishmanial Activity of Medicinal Plants Used in Endemic Areas in Northeastern Brazil

Figure 3

Antileishmanial effect of H. pectinata, A. vera, and R. graveolens against the replication of L. amazonensis promastigotes. The height of the bars indicates the parasite number at each concentration of plant aqueous extract compared with the control experiment containing only the solvent DMSO. Macrophages were infected with L. amazonensis promastigotes for 3 h. After infection, plant aqueous extracts were added at final concentrations of 100, 10, and 1 μg/mL for 4 days. After 4 days, the extracellular load of L. amazonensis was measured. The experiments were performed three times independently, and each count was performed in triplicate. The data are reported as the means ± S.E.M. Differences with 𝑃 values <0.05 were considered significant (^∗𝑃<0.05; ^∗∗𝑃<0.01).

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