Review Article

Adverse Events of Massage Therapy in Pain-Related Conditions: A Systematic Review

Table 2

Case series of AEs associated with massage therapy.

Author (year)CountryLanguageCasesDetails of manual therapyClinician typeAdverse event (nature and location)Follow-up

Young and Chen (2003) [50] TaiwanEnglish9Cervical manipulationChiropractorVertebral artery occlusion (1 case);
stenosis (1 case);
slow blood flow (1 case)
associated with normal findings (6 cases)
Recovered (3 mo.)

Mei et al. (2003) [51] ChinaChinese21Rotatory reduction manipulationNot mentionedNausea and profuse sweating (8 cases); headache and vertigo (5 cases); upper extremity numbness (4 cases); cervical limitation of activity (12 cases); lower limbs motor disturbance (5 cases)8 cases recovered,
13 cases improved

Oppenheim et al. (2005) [52] USAEnglish18Spinal manipulationChiropractorSpinal cord injuries (9 cases); cauda equina syndrome (2 cases); radiculopathy (6 cases); pathological fracture (3 cases)16 patients need surgery, but half of them made an excellent recovery subsequently, and one-third had a good recovery

Wang (2005) [53] ChinaChinese9Rotatory reduction manipulationNot mentionedLumbar intervertebral disc extrusionFully recovered (5 cases);
foot prolapse (3 cases);
hypoesthesia (1 case)

Wang et al. (2008) [54] ChinaChinese5Neck massageNot mentionedCervical disc herniationRecovered

Guo and Lu (2009) [55] ChinaChinese26Rotation (17 cases), tendon-regulating method (9 cases)Not mentionedSimple soft tissue injury (15 cases);
cervical structural damage (11 cases)
Not mentioned

Qu et al. (2010) [56] ChinaChinese7Pressing manipulationNot mentionedAggravated lumbar intervertebral disc extrusionRecovered (5–10 d.)