A Network Pharmacology Approach to Determine Active Compounds and Action Mechanisms of Ge-Gen-Qin-Lian Decoction for Treatment of Type 2 Diabetes

Table 2

Potential antidiabetic ingredients in Ge-Gen-Qin-Lian formula by network target analysis.

Ingredients	Herbs	CID	Literature evidence
4-Hydroxymephenytoin	Ge-Gen	119507	/
1-OCTEN-3-OL	Ge-Gen	18827	[50]
Berbericinine	Huang-Lian	19009	/
Berberine bisulfate	Huang-Lian	12457	[51]
Columbamine	Huang-Lian	72310	[52]
Coptisine	Huang-Lian	72322	[53]
Epiberberine	Huang-Lian	160876	[54, 55]
Jatrorrhizine	Huang-Lian	72323	[55, 56]
Oxyberberine	Huang-Lian	11066	[57]
Dehydrocheilanthifoline	Huang-Lian	3084708	[58]
Berberine	Huang-Lian	2353	[59]
Indole	Huang-Qin	798	[60]
1,3-Diphenylbenzene	Huang-Qin	7076	/
2-Formylpyrrole	Huang-Qin	13854	/
Guaifenesin	Huang-Qin	3516	[61]
1-(1H-Pyrrol-2-yl)ethanone	Gan-Cao	14079	[62]
2-Acetyl-1-methylpyrrole	Gan-Cao	61240	[63]
m-Ethylphenyl acetate	Gan-Cao	76462	/
5,6,7,8-Tetrahydro-4-methylquinoline	Gan-Cao	185667	/

/: no evidence.