Research Article
Analgesia Synergism of Essential Oil from Pericarp of Zanthoxylum schinifolium and Verapamil
Table 5
Effect of amplitude of action potential (AP) of sciatic nerve in toads (
,
).
| Group | Dosage (g/mL) | Preadmin/mV | Proadmin/mV | Time of AP vanishing | 1 min | 5 min | 10 min | min |
| RS | | 4.35 ± 1.25 | 4.26 ± 1.32 | 4.30 ± 1.16 | 4.33 ± 1.53 | exist | EOZ | 0.2% | 4.39 ± 1.43 |
3.21 ± 0.85①③ | 0 | 0 | 4.98 ± 0.92③ | Ver | 0.05% | 4.42 ± 1.02 | 4.39 ± 1.32 | 4.43 ± 1.06 | 4.29 ± 1.34 | exist | EOZ + Ver | 0.2% + 0.05% | 4.45 ± 1.03 | 2.36 ± 1.02②③ | 0 | 0 | 2.62 ± 0.58③⑤ | Lid | 1% | 4.53 ± 1.12 | 4.52 ± 1.35 | 4.50 ± 1.65①③ | 4.38 ± 1.65①③ | 22.89 ± 6.52③ |
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Compared with preadministration: ①: , ②: ; compared with NS group: ③: , ④: ; compared with EOZ group: ⑤: .
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