Ginseng Total Saponins Reverse Corticosterone-Induced Changes in Depression-Like Behavior and Hippocampal Plasticity-Related Proteins by Interfering with GSK-3<b><i>β</i></b>-CREB Signaling Pathway

<table>Effects of fluoxetine or different doses of ginseng total saponins on serum corticosterone in the corticosterone-induced mouse depression model. **<svg height="11.375" id="M38" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 58.712502 11.375" width="58.712502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> versus the CORT group; <sup>##</sup><svg height="11.375" id="M39" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 58.712502 11.375" width="58.712502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> versus the control group.</table>

Evidence-Based Complementary and Alternative Medicine

fig4

Figure 4

Figure 4: Ginseng Total Saponins Reverse Corticosterone-Induced Changes in Depression-Like Behavior and Hippocampal Plasticity-Related Proteins by Interfering with GSK-3<b><i>β</i></b>-CREB Signaling Pathway 

Figure 4 | Ginseng Total Saponins Reverse Corticosterone-Induced Changes in Depression-Like Behavior and Hippocampal Plasticity-Related Proteins by Interfering with GSK-3β-CREB Signaling Pathway 