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Evidence-Based Complementary and Alternative Medicine
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Special Issues
Evidence-Based Complementary and Alternative Medicine
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2014
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Article
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Tab 3
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Research Article
A Platform for Screening Potential Anticholinesterase Fractions and Components Obtained from
Anemarrhena asphodeloides
Bge for Treating Alzheimer’s Disease
Table 3
The effects of the twenty-five compounds on AChE and BuChE inhibitory activities.
Compounds
AChE inhibition (%)
BuChE inhibition (%)
1
17.9 ± 0.3
37.6 ± 0.6
2
15.2 ± 0.2
28.1 ± 0.4
3
12.5 ± 0.4
75.8 ± 0.7
4
—
—
5
14.1 ± 0.3
35.3 ± 0.5
6
17.9 ± 0.2
36.0 ± 0.4
7
14.2 ± 0.5
0.6 ± 0.1
8
—
—
9
—
—
10
0.9 ± 0.1
0.1 ± 0.1
11
7.9 ± 0.3
4.0 ± 0.2
12
1.7 ± 0.2
15.1 ± 0.3
13
18.5 ± 0.4
0.5 ± 0.1
14
27.2 ± 0.2
4.2 ± 0.2
15
21.6 ± 0.4
—
16
1.1 ± 0.1
—
17
13.2 ± 0.3
—
18
15.9 ± 0.4
—
19
23.5 ± 0.4
12.3 ± 0.6
20
18.4 ± 0.4
—
21
19.2 ± 0.3
—
22
17.3 ± 0.3
—
23
20.3 ± 0.5
7.3 ± 0.2
24
21.1 ± 0.6
—
25
22.4 ± 0.2
2.8 ± 0.2
Donepezil
98.2 ± 0.8
79.8 ± 0.7